Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GFER | P55789 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GHSR | Q92847 | 1/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31679833 | 0.84 | LMNA (0.50) | LCKKDRAPPMAPTTDP1 | |
| SCHEMBL31679983 | 0.78 | LMNA (0.48) | LCKKDRAPPMAPTTDP1 | |
| SCHEMBL31679936 | 0.78 | LMNA (0.63) | MAPTPOLBGAAKMT2AMEN1 | |
| SCHEMBL24876599 | 0.78 | LMNA (0.48) | LCKKDRAPPMAPTTDP1 | |
| SCHEMBL24876379 | 0.78 | LMNA (0.63) | MAPTPOLBGAAKMT2AMEN1 | |
| SCHEMBL31679842 | 0.76 | LMNA (0.63) | MAPTPOLBGAAKMT2AMEN1 | |
| SCHEMBL24876074 | 0.72 | LMNA (0.60) | LCKKDRMAPTPOLBGAA | |
| SCHEMBL31679964 | 0.72 | LMNA (0.60) | LCKKDRMAPTPOLBGAA | |
| SCHEMBL24876629 | 0.72 | HSD17B2 (0.43) | MAPTTDP1KMT2AMEN1LMNA | |
| SCHEMBL24876266 | 0.68 | CDK1 (0.48) | ALDH1A1GAAKMT2AGFERHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280970-A1 | INHIBITORS OF ALPHA-HEMOLYSIN OF STAPHYLOCOCCUS AUREUS | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2023-01-12 | — | — | WO | disclosed |