Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | THRB | P10828 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 8/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24876646 | 0.85 | LMNA (0.65) | LMNAMEN1KMT2AALDH1A1THRB | |
| SCHEMBL31679802 | 0.85 | LMNA (0.55) | LMNAMEN1KMT2AALDH1A1THRB | |
| SCHEMBL24876656 | 0.83 | LMNA (0.65) | LMNAMEN1KMT2AALDH1A1THRB | |
| SCHEMBL24876161 | 0.78 | KMT2A (0.55) | LMNAMEN1KMT2ATHRBSMN1; SMN2 | |
| SCHEMBL31679999 | 0.77 | MEN1 (0.47) | LMNAMEN1KMT2AALDH1A1THRB | |
| SCHEMBL24876751 | 0.76 | LMNA (0.48) | LMNAMEN1KMT2AALDH1A1THRB | |
| SCHEMBL24876746 | 0.76 | ACLY (0.56) | LMNAMEN1KMT2ATHRBPKM | |
| SCHEMBL31679859 | 0.76 | THRB (0.57) | LMNAMEN1KMT2ATHRBPKM | |
| SCHEMBL24876665 | 0.76 | THRB (0.57) | LMNAMEN1KMT2ATHRBPKM | |
| SCHEMBL24876015 | 0.76 | MEN1 (0.61) | LMNAMEN1KMT2AALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4367103-B1 | INHIBITORS OF ALPHA-HEMOLYSIN OF STAPHYLOCOCCUS AUREUS | HELMHOLTZ ZENTRUM INFEKTIONSFORSCHUNG GMBH (DE) | 2025-09-03 | — | — | EP | disclosed |
| WO-2023280970-A1 | INHIBITORS OF ALPHA-HEMOLYSIN OF STAPHYLOCOCCUS AUREUS | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2023-01-12 | — | — | WO | disclosed |