Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.43 |
| ▸ | DRD3 | P35462 | 4/20 | 0.43 |
| ▸ | PNMT | P11086 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 2/20 | 0.38 |
| ▸ | BACE1 | P56817 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24878782 | 0.85 | HRH3 (0.42) | DRD2DRD3PNMTHRH3KDM1A | |
| SCHEMBL29550707 | 0.81 | TSHR (0.42) | — | |
| SCHEMBL29506141 | 0.80 | PNMT (0.49) | DRD2DRD3PNMTKDM1A | |
| SCHEMBL22789739 | 0.80 | PNMT (0.49) | DRD2DRD3PNMTKDM1A | |
| SCHEMBL24282578 | 0.77 | GPR119 (0.47) | — | |
| SCHEMBL24388844 | 0.76 | OPRM1 (0.40) | RAB9AOPRM1 | |
| SCHEMBL12715536 | 0.75 | POLB (0.46) | DRD2DRD3PNMTKDM1A | |
| SCHEMBL29506198 | 0.75 | THRB (0.44) | — | |
| SCHEMBL30081409 | 0.75 | THRB (0.44) | — | |
| SCHEMBL24388817 | 0.75 | KDM4E (0.40) | RAB9AOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023282702-A1 | SHP2 INHIBITOR AND USE THEREOF | 주식회사 카나프테라퓨틱스 | 2023-01-12 | — | — | WO | disclosed |