Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMP1 | P13497 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 2/20 | 0.42 |
| ▸ | MMP9 | P14780 | 2/20 | 0.42 |
| ▸ | MMP13 | P45452 | 2/20 | 0.42 |
| ▸ | ACP1 | P24666 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | FBP1 | P09467 | 1/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29438912 | 0.88 | MMP9 (0.43) | BMP1KMT2ACA12CA1CA2 | |
| SCHEMBL22718087 | 0.88 | MMP9 (0.43) | BMP1KMT2ACA12CA1CA2 | |
| SCHEMBL30114488 | 0.86 | BMP1 (0.60) | BMP1KMT2AMMP1MMP9MMP13 | |
| SCHEMBL22718099 | 0.86 | BMP1 (0.46) | BMP1KMT2ACA12CA1CA2 | |
| SCHEMBL22718201 | 0.86 | BMP1 (0.45) | BMP1KMT2ACA12CA1CA2 | |
| SCHEMBL22718415 | 0.85 | BMP1 (0.48) | BMP1KMT2ACA12CA1CA2 | |
| SCHEMBL22718311 | 0.85 | BMP1 (0.48) | BMP1KMT2ACA12CA1CA2 | |
| SCHEMBL22718312 | 0.85 | BMP1 (0.48) | BMP1KMT2ACA12CA1CA2 | |
| SCHEMBL24497433 | 0.84 | BMP1 (0.47) | BMP1KMT2AMMP1MMP9MMP13 | |
| SCHEMBL24496385 | 0.83 | BMP1 (0.43) | BMP1CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023016562-A1 | POLYCYCLIC COMPOUND AND USE THEREOF | 浙江同源康医药股份有限公司 | 2023-02-16 | — | — | WO | disclosed |
| CN-115594680-A | TEAD inhibitor | 武汉人福创新药物研发中心有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |
| WO-2023280254-A1 | TEAD INHIBITOR | 武汉人福创新药物研发中心有限公司 | 2023-01-12 | — | — | WO | disclosed |