Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 8/20 | 0.43 |
| ▸ | MMP13 | P45452 | 8/20 | 0.43 |
| ▸ | MMP1 | P03956 | 6/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | BMP1 | P13497 | 2/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ACP1 | P24666 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22718087 | 1.00 | MMP9 (0.43) | MMP9MMP13MMP1CA12CA1 | |
| SCHEMBL24880306 | 0.88 | BMP1 (0.52) | MMP9MMP13MMP1CA12CA1 | |
| SCHEMBL22718201 | 0.85 | BMP1 (0.45) | MMP9MMP13MMP1CA12CA1 | |
| SCHEMBL22843409 | 0.84 | CYP2C9 (0.37) | CA2KDM4EMEN1KMT2A | |
| SCHEMBL22718297 | 0.84 | CA12 (0.42) | MMP9MMP13MMP1CA12CA1 | |
| SCHEMBL29438885 | 0.84 | CA12 (0.42) | MMP9MMP13MMP1CA12CA1 | |
| SCHEMBL22718099 | 0.84 | BMP1 (0.46) | MMP9MMP13MMP1CA12CA1 | |
| SCHEMBL22718146 | 0.83 | TEAD1 (0.51) | MMP9MMP13MMP1BMP1KDM4E | |
| SCHEMBL29438859 | 0.83 | TEAD1 (0.51) | MMP9MMP13MMP1BMP1KDM4E | |
| SCHEMBL24496385 | 0.83 | BMP1 (0.43) | MMP9MMP13MMP1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119954725-A | TEAD inhibitors and uses thereof | 医肯纳肿瘤学公司 | 2025-05-09 | — | — | CN | disclosed |
| CN-114466839-B | TEAD inhibitors and uses thereof | 医肯纳肿瘤学公司 | 2025-01-07 | — | — | CN | disclosed |
| EP-3976194-A2 | TEAD INHIBITORS AND USES THEREOF | Ikena Oncology, Inc. (US) | 2022-04-06 | — | — | EP | disclosed |