Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16552753 | 0.80 | MAPT (0.36) | L3MBTL1KDM1AMAPTRAB9A | |
| SCHEMBL463113 | 0.69 | — | — | |
| SCHEMBL11776737 | 0.69 | — | — | |
| SCHEMBL11838176 | 0.69 | — | — | |
| SCHEMBL20819269 | 0.67 | — | — | |
| SCHEMBL31487633 | 0.67 | — | — | |
| SCHEMBL692444 | 0.66 | L3MBTL1 (0.58) | L3MBTL1TP53ALDH1A1HPGDMAPK1 | |
| SCHEMBL20819321 | 0.66 | KDM4E (0.32) | HPGDMAPTMEN1KMT2AKDM4E | |
| SCHEMBL1950950 | 0.65 | L3MBTL1 (0.52) | L3MBTL1TP53ALDH1A1HPGDPOLB | |
| SCHEMBL8077426 | 0.64 | ALDH1A1 (0.38) | L3MBTL1ALDH1A1MAPK1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9376402-B2 | 1, 2, 4-triazole derivatives and their anti-microbial activity | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-06-28 | — | — | US | claimed |
| US-20150073026-A1 | 1, 2, 4-TRIAZOLE DERIVATIVES AND THEIR ANTI-MICROBIAL ACTIVITY | COUNCIL SCIENT IND RES (IN) | 2015-03-12 | — | — | US | claimed |
| US-20130060045-A1 | 1, 2, 4-TRIAZOLE DERIVATIVES AND THEIR ANTI MYCOBACTERIAL ACTIVITY | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2013-03-07 | — | — | US | claimed |
| US-9376402-B2 | 1, 2, 4-triazole derivatives and their anti-microbial activity | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-06-28 | — | — | US | disclosed |
| US-9376402-B2 | 1, 2, 4-triazole derivatives and their anti-microbial activity | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-06-28 | — | — | US | disclosed |
| US-9376402-B2 | 1, 2, 4-triazole derivatives and their anti-microbial activity | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-06-28 | — | — | US | disclosed |
| US-20150073026-A1 | 1, 2, 4-TRIAZOLE DERIVATIVES AND THEIR ANTI-MICROBIAL ACTIVITY | COUNCIL SCIENT IND RES (IN) | 2015-03-12 | — | — | US | disclosed |
| US-20150073026-A1 | 1, 2, 4-TRIAZOLE DERIVATIVES AND THEIR ANTI-MICROBIAL ACTIVITY | COUNCIL SCIENT IND RES (IN) | 2015-03-12 | — | — | US | disclosed |
| US-20150073026-A1 | 1, 2, 4-TRIAZOLE DERIVATIVES AND THEIR ANTI-MICROBIAL ACTIVITY | COUNCIL SCIENT IND RES (IN) | 2015-03-12 | — | — | US | disclosed |
| US-8865910-B2 | 1, 2, 4-triazole derivatives and their anti mycobacterial activity | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2014-10-21 | — | — | US | disclosed |
| US-8865910-B2 | 1, 2, 4-triazole derivatives and their anti mycobacterial activity | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2014-10-21 | — | — | US | disclosed |
| US-8865910-B2 | 1, 2, 4-triazole derivatives and their anti mycobacterial activity | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2014-10-21 | — | — | US | disclosed |
| US-20130060045-A1 | 1, 2, 4-TRIAZOLE DERIVATIVES AND THEIR ANTI MYCOBACTERIAL ACTIVITY | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2013-03-07 | — | — | US | disclosed |
| US-20130060045-A1 | 1, 2, 4-TRIAZOLE DERIVATIVES AND THEIR ANTI MYCOBACTERIAL ACTIVITY | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2013-03-07 | — | — | US | disclosed |
| US-20130060045-A1 | 1, 2, 4-TRIAZOLE DERIVATIVES AND THEIR ANTI MYCOBACTERIAL ACTIVITY | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2013-03-07 | — | — | US | disclosed |
| WO-2011111077-A1 | 1, 2, 4-TRIAZOLE DERIVATIVES AND THEIR ANTI MYCOBACTERIAL ACTIVITY | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2011-09-15 | — | — | WO | disclosed |
| WO-2011111077-A1 | 1, 2, 4-TRIAZOLE DERIVATIVES AND THEIR ANTI MYCOBACTERIAL ACTIVITY | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2011-09-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130060045-A1 | 1, 2, 4-TRIAZOLE DERIVATIVES AND THEIR ANTI MYCOBACTERIAL ACTIVITY | NAT1, CBR3, NOX3 | L3MBTL1 324/4885TP53 4732/4885ALDH1A1 838/4885 |
| US-20150073026-A1 | 1, 2, 4-TRIAZOLE DERIVATIVES AND THEIR ANTI-MICROBIAL ACTIVITY | CYP51A1, TALDO1, IL33 | L3MBTL1 3436/4885TP53 2518/4885ALDH1A1 2013/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.