SCHEMBL2489063

SCHEMBL2489063

Nc1c(O)cccc1S

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL69654 0.80
SCHEMBL9739116 0.80 SMN1; SMN2 (0.42)
Hydrochloric Acid SCHEMBL766671 0.77 G6PD (0.54)
SCHEMBL10166787 0.74 IDO1 (0.52)
SCHEMBL190980 0.72
SCHEMBL564030 0.72 CASP7 (0.50)
SCHEMBL29623283 0.72
SCHEMBL6755335 0.72 ALDH1A1 (0.36)
SCHEMBL753611 0.72
SCHEMBL296442 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2380021-A1 A SENSOR SPHERE Medical Limited (GB) 2011-10-26 EP claimed
WO-2010015859-A1 A SENSOR SPHERE MEDICAL LIMITED (GB) 2010-02-11 WO claimed
US-20060022177-A1 Nanoparticulate organc uv absorber BASF AKTIENGESELLSCHAFT (DE) 2006-02-02 US claimed
EP-1499659-A1 NANOPARTICULATE ORGANIC UV ABSORBER BASF AKTIENGESELLSCHAFT (DE) 2005-01-26 EP claimed
WO-2003085033-A1 NANOPARTICULATE ORGANIC UV ABSORBER BASF AKTIENGESELLSCHAFT (DE) 2003-10-16 WO claimed
EP-0398425-B1 Antirhinoviral piperidinyl, pyrrolidinyl and piperazinyl alkylphenol ethers JANSSEN PHARMACEUTICA NV (BE) 1994-03-16 EP claimed
EP-0398425-A1 Antirhinoviral piperidinyl, pyrrolidinyl and piperazinyl alkylphenol ethers JANSSEN PHARMACEUTICA N.V. (BE) 1990-11-22 EP claimed
JP-62289569-A None JP disclosed
CN-117337317-A Multilayer barrier films, their manufacture and use in photovoltaic applications 巴斯夫涂料有限公司 2024-01-02 CN disclosed
CN-101600746-B Polyurethane adhesive LUCITE INTERNAT INC US 2012-08-29 CN disclosed
EP-2380021-A1 A SENSOR SPHERE Medical Limited (GB) 2011-10-26 EP disclosed
WO-2010015859-A1 A SENSOR SPHERE MEDICAL LIMITED (GB) 2010-02-11 WO disclosed
CN-101600746-A Polyurethane binder LUCITE INTERNAT INC (US) 2009-12-09 CN disclosed
EP-0398425-B1 Antirhinoviral piperidinyl, pyrrolidinyl and piperazinyl alkylphenol ethers JANSSEN PHARMACEUTICA NV (BE) 1994-03-16 EP disclosed
US-5281592-A Calcium antagonist, antiischemic agents, brains, nervous system disorders TANABE SEIYAKU CO., LTD. (JP) 1994-01-25 US disclosed
US-5246929-A Prophylaxis or treatment of ischemic encephalopathia TANABE SEIYAKU CO., LTD. (JP) 1993-09-21 US disclosed
EP-0441539-A2 Thiazine (or oxazine) derivatives and preparation thereof TANABE SEIYAKU CO., LTD. (JP) 1991-08-14 EP disclosed
EP-0398425-A1 Antirhinoviral piperidinyl, pyrrolidinyl and piperazinyl alkylphenol ethers JANSSEN PHARMACEUTICA N.V. (BE) 1990-11-22 EP disclosed
JP-S62289569-A FLUORINE-CONTAINING HETEROCYCLIC COMPOUND DAIKIN IND LTD 1987-12-16 JP disclosed
US-3984405-A PYRIDO(3,2-B)(1,4)OXAZIN-3(4H)-ONES E. R. SQUIBB & SONS, INC. (US) 1976-10-05 US disclosed