Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6755335 | 0.84 | ALDH1A1 (0.36) | SMN1; SMN2ALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL16986786 | 0.82 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1HPGDHSD17B10BCL2L1 | |
| SCHEMBL7148992 | 0.80 | HPGD (0.50) | SMN1; SMN2ALDH1A1HPGDHSD17B10BCL2L1 | |
| SCHEMBL2489063 | 0.80 | — | — | |
| SCHEMBL6875810 | 0.78 | ALOX15 (0.54) | SMN1; SMN2ALDH1A1HPGDHSD17B10BCL2L1 | |
| SCHEMBL28881715 | 0.78 | HPGD (0.48) | SMN1; SMN2ALDH1A1HPGDHSD17B10BCL2L1 | |
| SCHEMBL8663299 | 0.77 | ALDH1A1 (0.43) | SMN1; SMN2ALDH1A1HPGDHSD17B10BCL2L1 | |
| SCHEMBL18871176 | 0.75 | SMN1; SMN2 (0.42) | SMN1; SMN2ALDH1A1HPGDHSD17B10BCL2L1 | |
| SCHEMBL18871186 | 0.75 | ALDH1A1 (0.50) | SMN1; SMN2ALDH1A1HPGDHSD17B10BCL2L1 | |
| SCHEMBL564030 | 0.74 | CASP7 (0.50) | SMN1; SMN2ALDH1A1HPGDHSD17B10BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5093495-A | Benzoheterocyclic compounds | SHELL OIL COMPANY (US) | 1992-03-03 | — | — | US | disclosed |
| US-5071996-A | Benzheterocyclic compounds | SHELL OIL COMPANY (US) | 1991-12-10 | — | — | US | disclosed |