Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TMPRSS2 | O15393 | 2/20 | 0.43 |
| ▸ | QDPR | P09417 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 6/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24891885 | 0.88 | TMPRSS2 (0.45) | ALDH1A1HPGDTMPRSS2KDM4EMAPT | |
| SCHEMBL24669387 | 0.88 | TMPRSS2 (0.45) | ALDH1A1HPGDTMPRSS2KDM4EMAPT | |
| SCHEMBL24891766 | 0.87 | TMPRSS2 (0.47) | ALDH1A1HPGDTMPRSS2MAPTNAMPT | |
| SCHEMBL30181321 | 0.83 | TMPRSS2 (0.46) | ALDH1A1TMPRSS2NAMPT | |
| SCHEMBL30181076 | 0.82 | TMPRSS2 (0.42) | ALDH1A1HPGDTMPRSS2MAPTNAMPT | |
| SCHEMBL24891978 | 0.82 | TMPRSS2 (0.42) | ALDH1A1HPGDTMPRSS2MAPTNAMPT | |
| SCHEMBL24891773 | 0.82 | NAMPT (0.48) | ALDH1A1HPGDQDPRKDM4EMAPT | |
| SCHEMBL24891705 | 0.82 | NAMPT (0.43) | ALDH1A1TMPRSS2KDM4ENAMPT | |
| SCHEMBL24891666 | 0.82 | NAMPT (0.43) | ALDH1A1TMPRSS2KDM4ENAMPT | |
| SCHEMBL30181035 | 0.80 | NAMPT (0.43) | ALDH1A1TMPRSS2NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023287736-A1 | NOVEL BIS-AMIDE CONTAINING COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2023-01-19 | — | — | WO | claimed |
| WO-2023287736-A1 | NOVEL BIS-AMIDE CONTAINING COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2023-01-19 | — | — | WO | disclosed |
| WO-2023287736-A1 | NOVEL BIS-AMIDE CONTAINING COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2023-01-19 | — | — | WO | disclosed |