Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR3 | P25089 | 6/20 | 0.49 |
| ▸ | FPR2 | P25090 | 6/20 | 0.49 |
| ▸ | BCL2 | P10415 | 5/20 | 0.47 |
| ▸ | BECN1 | Q14457 | 5/20 | 0.47 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GHSR | Q92847 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24891966 | 0.87 | FPR3 (0.65) | FPR3FPR2MEN1KMT2A | |
| SCHEMBL467281 | 0.87 | KMT2A (0.56) | BCL2BECN1CYP17A1NPC1RAB9A | |
| SCHEMBL24892015 | 0.85 | NAMPT (0.56) | FPR3FPR2RAB9ADRD2SMN1; SMN2 | |
| SCHEMBL24891926 | 0.83 | FPR3 (0.63) | FPR3FPR2MEN1KMT2A | |
| SCHEMBL6235125 | 0.82 | FAAH (0.56) | FPR3FPR2NPC1RAB9AMEN1 | |
| SCHEMBL206442 | 0.82 | CYP17A1 (0.59) | BCL2BECN1CYP17A1NPC1RAB9A | |
| SCHEMBL24892032 | 0.81 | FPR2 (0.51) | FPR3FPR2BCL2BECN1KMT2A | |
| SCHEMBL30182265 | 0.80 | FPR3 (0.50) | FPR3FPR2MEN1KMT2AGHSR | |
| SCHEMBL24891994 | 0.80 | FPR3 (0.50) | FPR3FPR2MEN1KMT2AGHSR | |
| SCHEMBL6268190 | 0.80 | FAAH (0.63) | FPR3FPR2GHSRFAAHTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023287736-A1 | NOVEL BIS-AMIDE CONTAINING COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2023-01-19 | — | — | WO | disclosed |
| WO-2023287736-A1 | NOVEL BIS-AMIDE CONTAINING COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2023-01-19 | — | — | WO | disclosed |