Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.56 |
| ▸ | FPR2 | P25090 | 10/20 | 0.55 |
| ▸ | FPR3 | P25089 | 9/20 | 0.55 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30182484 | 0.93 | NAMPT (0.56) | NAMPTFPR2FPR3CNR1USP2 | |
| SCHEMBL24892366 | 0.90 | NAMPT (0.57) | NAMPTFPR2FPR3CA2CA1 | |
| SCHEMBL24891966 | 0.88 | FPR3 (0.65) | NAMPTFPR2FPR3CTSSCTSK | |
| SCHEMBL24891748 | 0.85 | FPR3 (0.49) | FPR2FPR3DRD2RAB9ASMN1; SMN2 | |
| SCHEMBL1065312 | 0.85 | CA2 (0.55) | NAMPTFPR2FPR3CNR1LMNA | |
| SCHEMBL24891960 | 0.85 | FPR2 (0.52) | NAMPTFPR2FPR3CNR1USP2 | |
| SCHEMBL24891926 | 0.84 | FPR3 (0.63) | NAMPTFPR2FPR3CTSSCTSK | |
| SCHEMBL24669430 | 0.84 | NAMPT (0.55) | NAMPTFPR2FPR3CNR1USP2 | |
| SCHEMBL24892005 | 0.82 | FPR2 (0.49) | NAMPTFPR2FPR3CNR1USP2 | |
| SCHEMBL24891956 | 0.81 | FPR3 (0.62) | NAMPTFPR2FPR3CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023287736-A1 | NOVEL BIS-AMIDE CONTAINING COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2023-01-19 | — | — | WO | disclosed |
| WO-2023287736-A1 | NOVEL BIS-AMIDE CONTAINING COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2023-01-19 | — | — | WO | disclosed |