SCHEMBL2489440

SCHEMBL2489440

Cc1cccc(C)c1O[P](=O)Oc1c(C)cccc1C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.38
KDM4E B2RXH2 1/20 0.38
HPGD P15428 1/20 0.38
HSD17B10 Q99714 1/20 0.38
SCN4A P35499 8/20 0.38
CYP1A2 P05177 3/20 0.38
LMNA P02545 2/20 0.38
TSHR P16473 2/20 0.38
SCN1A P35498 2/20 0.38
SCN5A Q14524 2/20 0.38
SCN9A Q15858 2/20 0.38
CYP3A4 P08684 2/20 0.38
CYP2D6 P10635 2/20 0.38
NFKB1 P19838 2/20 0.38
CYP2A6 P11509 1/20 0.38
CYP2C9 P11712 1/20 0.38
KCNK3 O14649 1/20 0.38
CACNA1F O60840 1/20 0.38
KCNK2 O95069 1/20 0.38
GBA1 P04062 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL123568 0.79 CYP1A2 (0.41) ALDH1A1KDM4EHPGDHSD17B10SCN4A
SCHEMBL11287658 0.75 ALDH1A1 (0.42) ALDH1A1KDM4EHPGDHSD17B10SCN4A
SCHEMBL1725363 0.75 SCN4A (0.38) ALDH1A1KDM4EHPGDHSD17B10SCN4A
SCHEMBL11585086 0.75 ALDH1A1 (0.42) ALDH1A1KDM4EHPGDHSD17B10SCN4A
SCHEMBL16461427 0.73 SCN4A (0.36) ALDH1A1KDM4EHPGDHSD17B10SCN4A
SCHEMBL19160166 0.71 L3MBTL1 (0.40) ALDH1A1KDM4EHPGDHSD17B10SCN4A
SCHEMBL28295132 0.70 CYP1A2 (0.43) ALDH1A1KDM4EHPGDHSD17B10SCN4A
SCHEMBL2777218 0.70 SCN4A (0.38) ALDH1A1KDM4EHPGDHSD17B10SCN4A
SCHEMBL437049 0.69 HSP90AA1 (0.50) ALDH1A1KDM4EHPGDHSD17B10SCN4A
SCHEMBL28295133 0.69 CYP1A2 (0.41) ALDH1A1KDM4EHPGDHSD17B10SCN4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2380948-B1 Method for preparing a phosphorus flame retardant composition DAIHACHI CHEM IND (JP) 2019-07-03 EP disclosed
EP-2987844-A1 FLAME-RETARDANT AGENT COMPOSITION AND FLAME-RETARDANT RESIN COMPOSITION CONTAINING SAME, AND MOLDED ARTICLE Daihachi Chemical Industry Co., Ltd. (JP) 2016-02-24 EP disclosed
US-20160039996-A1 FLAME-RETARDANT AGENT COMPOSITION AND FLAME-RETARDANT RESIN COMPOSITION CONTAINING SAME, AND MOLDED ARTICLE DAIHACHI CHEMICAL INDUSTRY CO., LTD. (JP) 2016-02-11 US disclosed
US-8822715-B2 Method for producing aromatic diphosphates DAIHACHI CHEMICAL INDUSTRY CO., LTD. (JP) 2014-09-02 US disclosed
EP-2592087-A1 METHOD FOR PRODUCING AROMATIC DIPHOSPHATES Daihachi Chemical Industry Co., Ltd. (JP) 2013-05-15 EP disclosed
US-20130090490-A1 METHOD FOR PRODUCING AROMATIC DIPHOSPHATES DAIHACHI CHEMICAL INDUSTRY CO., LTD. (JP) 2013-04-11 US disclosed
US-20110263767-A1 PHOSPHORUS FLAME RETARDANT, FLAME-RETARDANT RESIN COMPOSITION CONTAINING SAME, AND MOLDED BODY DAIHACHI CHEMICAL INDUSTRY CO., LTD. (JP) 2011-10-27 US disclosed
EP-2380948-A1 PHOSPHORUS FLAME RETARDANT, FLAME-RETARDANT RESIN COMPOSITION CONTAINING SAME, AND MOLDED BODY Daihachi Chemical Industry Co., Ltd. (JP) 2011-10-26 EP disclosed
EP-0509506-B1 Crystalline powders of aromatic diphosphates, their preparation and use DAIHACHI CHEM IND (JP) 1997-06-25 EP disclosed
EP-0509506-A2 Crystalline powders of aromatic diphosphates, their preparation and use DAIHACHI CHEMICAL INDUSTRY CO., LTD. (JP) 1992-10-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130090490-A1 METHOD FOR PRODUCING AROMATIC DIPHOSPHATES NUDT1, PAH, DHODH ALDH1A1 1505/4885KDM4E 1098/4885HPGD 588/4885
US-20110263767-A1 PHOSPHORUS FLAME RETARDANT, FLAME-RETARDANT RESIN COMPOSITION CONTAINING SAME, AND MOLDED BODY PFAS, FGFR4, FGFR1 ALDH1A1 1416/4885KDM4E 818/4885HPGD 3116/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.