Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 3/20 | 0.46 |
| ▸ | GBA1 | P04062 | 6/20 | 0.45 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.40 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25835937 | 0.89 | DRD2 (0.42) | EPHX2DRD2GBA1GGPS1 | |
| SCHEMBL24894086 | 0.89 | DRD2 (0.47) | EPHX2DRD2GBA1HRH4HRH3 | |
| SCHEMBL26421435 | 0.88 | FOLH1 (0.42) | EPHX2DRD2GBA1 | |
| SCHEMBL25978189 | 0.88 | GBA1 (0.48) | EPHX2DRD2GBA1HRH4HRH3 | |
| SCHEMBL25835931 | 0.86 | GBA1 (0.41) | EPHX2DRD2GBA1GGPS1 | |
| SCHEMBL22083577 | 0.86 | DRD2 (0.44) | EPHX2DRD2GBA1HDAC1 | |
| SCHEMBL24894084 | 0.85 | EPHX2 (0.51) | EPHX2DRD2GBA1HRH4HRH3 | |
| SCHEMBL25978195 | 0.84 | FOLH1 (0.44) | DRD2HDAC1 | |
| SCHEMBL25978193 | 0.84 | DRD2 (0.43) | EPHX2DRD2GBA1HRH4HRH3 | |
| SCHEMBL24916753 | 0.84 | EPHX2 (0.53) | EPHX2DRD2GBA1HRH4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023288015-A1 | M6PR CELL SURFACE RECEPTOR BINDING COMPOUNDS AND CONJUGATES | LYCIA THERAPEUTICS, INC. (US) | 2023-01-19 | — | — | WO | disclosed |