SCHEMBL25835937

SCHEMBL25835937

CCCCc1cn(CCOCCC(=O)NCCOCCNC(=O)CCOCCOCCOCCOCCNCCOCCOCCOCCOCCC(=O)NCCOCCNC(=O)CCOCCn2cc(CCCC)nn2)nn1

nearest known ligand 0.42

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 3/20 0.42
GBA1 P04062 6/20 0.41
EPHX2 P34913 1/20 0.41
OPRM1 P35372 1/20 0.40
FOLH1 Q04609 4/20 0.39
GGPS1 O95749 1/20 0.38
LGALS3 P17931 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25835931 0.91 GBA1 (0.41) DRD2GBA1EPHX2OPRM1FOLH1
SCHEMBL24894530 0.89 EPHX2 (0.47) DRD2GBA1EPHX2GGPS1
SCHEMBL22083577 0.88 DRD2 (0.44) DRD2GBA1EPHX2OPRM1FOLH1
SCHEMBL25835929 0.87 ALDH1A1 (0.51) DRD2GBA1EPHX2
SCHEMBL24894086 0.87 DRD2 (0.47) DRD2GBA1EPHX2GGPS1
SCHEMBL25978189 0.86 GBA1 (0.48) DRD2GBA1EPHX2GGPS1
SCHEMBL25835936 0.85 DRD2 (0.42) DRD2GBA1EPHX2OPRM1
SCHEMBL25978193 0.82 DRD2 (0.43) DRD2GBA1EPHX2FOLH1GGPS1
SCHEMBL26032013 0.81 DRD2 (0.41) DRD2GBA1EPHX2OPRM1FOLH1
SCHEMBL25495665 0.81 DRD2 (0.37) DRD2OPRM1FOLH1LGALS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230265429-A1 SKELETAL MUSCLE DELIVERY PLATFORMS AND METHODS OF USE THEREOF Arrowhead Pharmaceuticals, Inc. 2023-08-24 US disclosed
US-20230226193-A1 LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS Arrowhead Pharmaceuticals, Inc. 2023-07-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230226193-A1 LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS CPT1B, MUSK, MYLK2 DRD2 4154/4885GBA1 627/4885EPHX2 3168/4885
US-20230265429-A1 SKELETAL MUSCLE DELIVERY PLATFORMS AND METHODS OF USE THEREOF MUSK, MYLK2, TNNC1 DRD2 4285/4885GBA1 2176/4885EPHX2 4580/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.