SCHEMBL25835931

SCHEMBL25835931

CCCCc1cn(CCOCCC(=O)NCCOCCN)nn1

nearest known ligand 0.42

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GBA1 P04062 6/20 0.41
EPHX2 P34913 1/20 0.40
FOLH1 Q04609 5/20 0.40
DRD2 P14416 3/20 0.39
CNR2 P34972 1/20 0.38
OPRM1 P35372 1/20 0.38
GGPS1 O95749 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25835937 0.91 DRD2 (0.42) GBA1EPHX2FOLH1DRD2OPRM1
SCHEMBL24894530 0.86 EPHX2 (0.47) GBA1EPHX2DRD2GGPS1
SCHEMBL25835929 0.86 ALDH1A1 (0.51) GBA1EPHX2DRD2
SCHEMBL22083577 0.85 DRD2 (0.44) GBA1EPHX2FOLH1DRD2OPRM1
SCHEMBL24894086 0.84 DRD2 (0.47) GBA1EPHX2DRD2GGPS1
SCHEMBL25978189 0.83 GBA1 (0.48) GBA1EPHX2DRD2GGPS1
SCHEMBL25835936 0.82 DRD2 (0.42) GBA1EPHX2DRD2OPRM1
SCHEMBL16983600 0.81 FOLH1 (0.49) FOLH1
SCHEMBL25978193 0.80 DRD2 (0.43) GBA1EPHX2FOLH1DRD2GGPS1
SCHEMBL9905232 0.78 FOLH1 (0.39) FOLH1DRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230265429-A1 SKELETAL MUSCLE DELIVERY PLATFORMS AND METHODS OF USE THEREOF Arrowhead Pharmaceuticals, Inc. 2023-08-24 US disclosed
US-20230226193-A1 LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS Arrowhead Pharmaceuticals, Inc. 2023-07-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230226193-A1 LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS CPT1B, MUSK, MYLK2 GBA1 627/4885EPHX2 3168/4885FOLH1 499/4885
US-20230265429-A1 SKELETAL MUSCLE DELIVERY PLATFORMS AND METHODS OF USE THEREOF MUSK, MYLK2, TNNC1 GBA1 2176/4885EPHX2 4580/4885FOLH1 1902/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.