SCHEMBL2489501

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2493499	0.88	SLC6A1 (0.43)	RORCSLC6A1KIF11SLC6A11RAB9A
	SCHEMBL2492369	0.82	KIF11 (0.38)	KIF11HRH4CYP3A4
	SCHEMBL2491345	0.81	TK2 (0.38)	KIF11SLC6A11RAB9ANPC1HRH4
	SCHEMBL2490790	0.81	KIF11 (0.50)	SLC6A1KIF11SLC6A11KCNN4ALDH1A1
	SCHEMBL2489713	0.80	KIF11 (0.59)	SLC6A1KIF11ALDH1A1HRH4CYP2C9
	SCHEMBL2494966	0.78	SLC6A11 (0.43)	SLC6A1SLC6A11ALDH1A1CYP3A4
	SCHEMBL2492376	0.76	KIF11 (0.64)	SLC6A1KIF11SLC6A11KCNN4ALDH1A1
	SCHEMBL5967728	0.75	KIF11 (0.49)	SLC6A1KIF11HRH4CYP2C9CYP2C19
	SCHEMBL8868959	0.74	KIF11 (0.57)	SLC6A1KIF11ALDH1A1HRH4CYP2C9
	SCHEMBL914263	0.73	KIF11 (0.55)	SLC6A1KIF11ALDH1A1HRH4CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.