SCHEMBL2493499

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2489501	0.88	RORC (0.42)	SLC6A1KIF11SLC6A11KCNN4SMN1; SMN2
	SCHEMBL2494532	0.81	KIF11 (0.41)	KIF11ALDH1A1RAB9ACYP3A4NPC1
	SCHEMBL2492376	0.79	KIF11 (0.64)	SLC6A1KIF11SLC6A11KCNN4SMN1; SMN2
	SCHEMBL2490812	0.79	KIF11 (0.39)	KIF11SLC6A11TNKSPARP1TNKS2
	SCHEMBL2491921	0.78	KIF11 (0.63)	SLC6A1KIF11ALDH1A1CYP2C9CYP2C19
	SCHEMBL2491594	0.76	SLC6A11 (0.45)	SLC6A1SLC6A11SMN1; SMN2ALDH1A1CYP3A4
	SCHEMBL2490790	0.76	KIF11 (0.50)	SLC6A1KIF11SLC6A11KCNN4SMN1; SMN2
	SCHEMBL12199493	0.73	KIF11 (0.52)	KIF11ALDH1A1
	SCHEMBL2490410	0.71	SLC6A11 (0.50)	SLC6A1KIF11SLC6A11CYP3A4
	SCHEMBL992028	0.71	SLC6A11 (0.50)	SLC6A1KIF11SLC6A11CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.