Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.53 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.51 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.51 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.51 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26844895 | 0.85 | PDK1 (0.50) | MMP8HDAC1HDAC7HDAC8HDAC6 | |
| SCHEMBL8322930 | 0.83 | PDK1 (0.60) | MMP8HDAC1HDAC7HDAC8HDAC6 | |
| SCHEMBL12890688 | 0.83 | PDK1 (0.51) | MMP8HDAC1HDAC7HDAC8HDAC6 | |
| SCHEMBL24895407 | 0.82 | HDAC1 (0.46) | MMP8HDAC1HDAC7HDAC8HDAC6 | |
| SCHEMBL750651 | 0.80 | RIPK1 (0.59) | MMP8HDAC1HDAC7HDAC8HDAC6 | |
| SCHEMBL3295838 | 0.80 | PDK1 (0.61) | MMP8HDAC1HDAC7HDAC8HDAC6 | |
| SCHEMBL8321463 | 0.80 | PDK1 (0.61) | MMP8HDAC1HDAC7HDAC8HDAC6 | |
| SCHEMBL383023 | 0.79 | HTT (0.66) | MMP8HDAC1HDAC7HDAC8HDAC6 | |
| SCHEMBL26499202 | 0.78 | PDK1 (0.46) | MMP8HDAC1HDAC7HDAC8HDAC6 | |
| SCHEMBL7440675 | 0.77 | MEN1 (0.71) | MMP8HDAC1HDAC7HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023287984-A1 | SUBEROYLANILIDE HYDROXAMIC ACID (SAHA) DRUGS, CONJUGATES, AND NANOPARTICLES, AND METHODS OF USE THEREOF | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2023-01-19 | — | — | WO | disclosed |