Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 6/20 | 0.60 |
| ▸ | PDK2 | Q15119 | 6/20 | 0.60 |
| ▸ | PDK3 | Q15120 | 6/20 | 0.60 |
| ▸ | PDK4 | Q16654 | 6/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.49 |
| ▸ | ABCC9 | O60706 | 3/20 | 0.48 |
| ▸ | ABCC8 | Q09428 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27587770 | 0.85 | PDK1 (0.63) | PDK1PDK2PDK3PDK4MMP8 | |
| SCHEMBL8321463 | 0.84 | PDK1 (0.61) | PDK1PDK2PDK3PDK4HTT | |
| SCHEMBL11874543 | 0.83 | PDK1 (0.57) | PDK1PDK2PDK3PDK4HTT | |
| SCHEMBL24895360 | 0.83 | MMP8 (0.60) | PDK1PDK2PDK3PDK4HTT | |
| SCHEMBL12890688 | 0.83 | PDK1 (0.51) | PDK1PDK2PDK3PDK4HTT | |
| SCHEMBL26844895 | 0.81 | PDK1 (0.50) | PDK1PDK2PDK3PDK4HTT | |
| SCHEMBL8575413 | 0.81 | PDK1 (0.54) | PDK1PDK2PDK3PDK4HTT | |
| SCHEMBL750651 | 0.80 | RIPK1 (0.59) | PDK1PDK2PDK3PDK4HTT | |
| SCHEMBL3295838 | 0.80 | PDK1 (0.61) | PDK1PDK2PDK3PDK4HTT | |
| SCHEMBL16212234 | 0.80 | PDK1 (0.70) | PDK1PDK2PDK3PDK4HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101891663-A | Preparation method of bicalutamide intermediate | Hangzhou minsheng pharmaceutical group co ltd | 2010-11-24 | — | — | CN | disclosed |
| US-5965735-A | Process for preparing flunixin and intermediates thereof | SCHERING CORPORATION (US) | 1999-10-12 | — | — | US | disclosed |
| US-5484931-A | Process for preparing Flunixin and intermediates thereof | SCHERING CORPORATION (US) | 1996-01-16 | — | — | US | disclosed |
| EP-0619809-B1 | PROCESS FOR PREPARING FLUNIXIN AND INTERMEDIATES THEREOF | SCHERING CORP (US) | 1995-11-02 | — | — | EP | disclosed |
| EP-0619809-A1 | PROCESS FOR PREPARING FLUNIXIN AND INTERMEDIATES THEREOF. | SCHERING CORP (US) | 1994-10-19 | — | — | EP | disclosed |
| WO-1993013070-A1 | PROCESS FOR PREPARING FLUNIXIN AND INTERMEDIATES THEREOF | SCHERING CORPORATION (US) | 1993-07-08 | — | — | WO | disclosed |