Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 3/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.34 |
| ▸ | EDNRB | P24530 | 4/20 | 0.33 |
| ▸ | FPR1 | P21462 | 3/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.32 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KLK7 | P49862 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2489935 | 0.91 | MGAM (0.33) | FFAR1 | |
| SCHEMBL2461978 | 0.79 | CHRM1 (0.40) | CHRM1PTGS2MAOBMTNR1AMTNR1B | |
| SCHEMBL2464167 | 0.78 | ESR1 (0.34) | PTGS2GRIA2GRIA4MTNR1AMTNR1B | |
| SCHEMBL2462829 | 0.78 | GRIA2 (0.44) | CHRM1PTGS2GRIA2GRIA4MAOB | |
| SCHEMBL2488207 | 0.75 | CHRM1 (0.41) | CHRM1PTGS2MAOBMTNR1AMTNR1B | |
| SCHEMBL15472265 | 0.73 | CHRM1 (0.43) | CHRM1PTGS2MAOBMAOAKDM4E | |
| SCHEMBL1135918 | 0.72 | CHRM1 (0.40) | CHRM1MAOBMAOAKDM4EALDH1A1 | |
| SCHEMBL1136167 | 0.72 | MAOB (0.39) | PTGS2MAOBMAOA | |
| SCHEMBL2581807 | 0.72 | CHRM1 (0.45) | CHRM1PTGS2MAOBFFAR1PPARD | |
| SCHEMBL2491673 | 0.72 | CHRM1 (0.42) | CHRM1PTGS2MAOBMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364298-A1 | Quinolone compound and pharmaceutical composition | Otsuka Pharmaceutical Co., Ltd. (JP) | 2011-09-14 | — | — | EP | disclosed |