SCHEMBL2462829

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2489539	0.78	CHRM1 (0.37)	GRIA2GRIA4CHRM1EDNRBPTGS2
	SCHEMBL2461285	0.77	PTGS2 (0.40)	CHRM1EDNRBPTGS2KDM4EALDH1A1
	SCHEMBL1135918	0.76	CHRM1 (0.40)	CHRM1KDM4EALDH1A1KMT2AMAOB
	SCHEMBL2458294	0.76	CHRM1 (0.43)	CHRM1PTGS2FFAR1KDM4EALDH1A1
	SCHEMBL2581807	0.76	CHRM1 (0.45)	CHRM1PTGS2FFAR1PPARDMAOB
	SCHEMBL3663892	0.76	CHRM1 (0.39)	CHRM1KDM4EALDH1A1KMT2AMAOB
	SCHEMBL2488207	0.75	CHRM1 (0.41)	CHRM1PTGS2FFAR1KDM4EPPARD
	SCHEMBL2463173	0.75	CHRM1 (0.42)	CHRM1PTGS2FFAR1KDM4EALDH1A1
	SCHEMBL3663890	0.75	CHRM1 (0.39)	CHRM1KDM4EALDH1A1KMT2AMAOB
	SCHEMBL15472265	0.75	CHRM1 (0.43)	CHRM1PTGS2KDM4EALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.