Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 5/20 | 0.33 |
| ▸ | GAA | P10253 | 5/20 | 0.33 |
| ▸ | SI | P14410 | 5/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 5/20 | 0.33 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | PREP | P48147 | 2/20 | 0.30 |
| ▸ | CELA1 | Q9UNI1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2489539 | 0.91 | CHRM1 (0.37) | FFAR1 | |
| SCHEMBL2460915 | 0.79 | MGAM (0.34) | MGAMGAASIMGAM2ACE2 | |
| SCHEMBL2461978 | 0.71 | CHRM1 (0.40) | MGAMGAASIMGAM2FFAR1 | |
| SCHEMBL27844048 | 0.71 | MET (0.33) | MGAMGAASIMGAM2ACE2 | |
| SCHEMBL2581722 | 0.71 | MGAM (0.34) | MGAMGAASIMGAM2ACE2 | |
| SCHEMBL2464167 | 0.69 | ESR1 (0.34) | — | |
| SCHEMBL2581745 | 0.69 | MGAM (0.36) | MGAMGAASIMGAM2ACE2 | |
| SCHEMBL2489936 | 0.69 | PIN1 (0.37) | MGAMGAASIMGAM2 | |
| SCHEMBL2462829 | 0.68 | GRIA2 (0.44) | FFAR1 | |
| SCHEMBL2461073 | 0.65 | SMN1; SMN2 (0.39) | MGAMGAASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364298-A1 | Quinolone compound and pharmaceutical composition | Otsuka Pharmaceutical Co., Ltd. (JP) | 2011-09-14 | — | — | EP | disclosed |