Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 3/20 | 0.43 |
| ▸ | CTSS | P25774 | 2/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24895884 | 0.90 | MAPT (0.49) | CYP3A4MAPTTHRBUSP30LMNA | |
| SCHEMBL24895389 | 0.90 | CYP3A4 (0.46) | CYP3A4MAPTTHRBUSP30LMNA | |
| SCHEMBL12919539 | 0.88 | CYP3A4 (0.58) | CYP3A4CNR2CNR1RECQL | |
| SCHEMBL24895875 | 0.86 | THRB (0.45) | CYP3A4MAPTTHRBUSP30LMNA | |
| SCHEMBL24895493 | 0.86 | CYP3A4 (0.43) | CYP3A4CNR1MAPTTHRBUSP30 | |
| SCHEMBL24895545 | 0.86 | CYP3A4 (0.43) | CYP3A4CNR1MAPTTHRBUSP30 | |
| SCHEMBL24895872 | 0.86 | THRB (0.49) | CYP3A4CNR2CNR1MAPTTHRB | |
| SCHEMBL17803363 | 0.85 | HSD11B1 (0.45) | DRD2SLC6A4HSD11B1CTSSCNR1 | |
| SCHEMBL17803221 | 0.85 | CTSS (0.52) | DRD2SLC6A4HSD11B1CTSSCNR1 | |
| SCHEMBL24895558 | 0.84 | DRD2 (0.57) | CYP3A4DRD2SLC6A4CNR2CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023284834-A1 | PIPERIDINE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION THEREOF, PREPARATION METHOD THEREFOR, AND USE THEREOF | 宜昌人福药业有限责任公司 | 2023-01-19 | — | — | WO | disclosed |