Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 4/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24896464 | 0.81 | KDM4E (0.39) | KMOFFAR4GRM4 | |
| SCHEMBL24896340 | 0.76 | LMNA (0.35) | KMO | |
| SCHEMBL24896466 | 0.72 | KLKB1 (0.37) | KMOFFAR4GRM4 | |
| SCHEMBL30220512 | 0.71 | MAOA (0.38) | — | |
| SCHEMBL24896382 | 0.68 | GRM4 (0.35) | GRM4IRAK4 | |
| SCHEMBL24896463 | 0.65 | LRRK2 (0.38) | GRM4LRRK2 | |
| SCHEMBL24896339 | 0.65 | CCR2 (0.51) | — | |
| SCHEMBL30220598 | 0.64 | DGAT1 (0.40) | — | |
| SCHEMBL24896258 | 0.64 | KDM4E (0.50) | — | |
| SCHEMBL21491015 | 0.62 | MDM2 (0.39) | IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023287704-A1 | BICYCLIC COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | NIDO BIOSCIENCES, INC. (US) | 2023-01-19 | — | — | WO | disclosed |