Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.51 |
| ▸ | MME | P08473 | 5/20 | 0.50 |
| ▸ | ACE | P12821 | 5/20 | 0.50 |
| ▸ | CPA1 | P15085 | 5/20 | 0.50 |
| ▸ | ACE2 | Q9BYF1 | 5/20 | 0.50 |
| ▸ | CTSS | P25774 | 4/20 | 0.50 |
| ▸ | CTSK | P43235 | 3/20 | 0.50 |
| ▸ | CTSB | P07858 | 2/20 | 0.50 |
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7903892 | 0.82 | MME (0.66) | MMEACECPA1ACE2 | |
| SCHEMBL7901632 | 0.82 | MME (0.66) | MMEACECPA1ACE2 | |
| SCHEMBL24760230 | 0.82 | CTSS (0.55) | CTSSCTSKCTSBCTSLOPRD1 | |
| SCHEMBL23937555 | 0.82 | CTSS (0.55) | CTSSCTSKCTSBCTSLOPRD1 | |
| SCHEMBL14416295 | 0.82 | PSMB5 (0.48) | L3MBTL1PSMB5MMEACECPA1 | |
| SCHEMBL13886178 | 0.81 | PSMB5 (0.61) | L3MBTL1PSMB5MMEACECPA1 | |
| SCHEMBL24899372 | 0.80 | HPGDS (0.56) | PSMB5MMEACECPA1ACE2 | |
| SCHEMBL14416298 | 0.80 | CYP1A2 (0.51) | MMEACECPA1ACE2CTSK | |
| SCHEMBL27761115 | 0.79 | HDAC1 (0.69) | L3MBTL1 | |
| SCHEMBL23154438 | 0.79 | L3MBTL1 (0.68) | L3MBTL1PSMB5CTSSCTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023288213-A1 | MACROCYCLIC IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-01-19 | — | — | WO | disclosed |