Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 2/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5981601 | 0.86 | MTNR1B (0.44) | MTNR1BCHRM2CHRM1CHRM3 | |
| SCHEMBL24915821 | 0.84 | APP (0.41) | MTNR1BAPP | |
| SCHEMBL20322844 | 0.79 | CTSS (0.50) | — | |
| SCHEMBL2723926 | 0.77 | LDHA (0.54) | — | |
| SCHEMBL5981533 | 0.77 | AAK1 (0.56) | MTNR1B | |
| SCHEMBL17118196 | 0.77 | SCN9A (0.51) | — | |
| SCHEMBL21029380 | 0.75 | KIF11 (0.42) | MTNR1B | |
| SCHEMBL23841532 | 0.75 | GAA (0.53) | MTNR1BCHRM2CHRM1CHRM3 | |
| SCHEMBL18867917 | 0.75 | GAA (0.53) | MTNR1BCHRM2CHRM1CHRM3 | |
| SCHEMBL19428705 | 0.75 | AAK1 (0.46) | APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024059472-A1 | MACROCYCLIC IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-03-21 | — | — | WO | disclosed |
| WO-2023288213-A1 | MACROCYCLIC IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-01-19 | — | — | WO | disclosed |