SCHEMBL24899753

SCHEMBL24899753

CCP(=O)(CC)c1ccc(I)cc1

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.31
TSHR P16473 2/20 0.31
LMNA P02545 2/20 0.31
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
PKM P14618 1/20 0.31
KMT2A Q03164 1/20 0.31
HPGD P15428 1/20 0.31
TPMT P51580 1/20 0.31
PYCR1 P32322 1/20 0.31
SIGMAR1 Q99720 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2033420 0.76 GAA (0.40) GAATSHRLMNAMEN1ALDH1A1
SCHEMBL19297523 0.76 CYP2A6 (0.38) GAAMEN1ALDH1A1KMT2A
SCHEMBL778908 0.75 ALDH1A1 (0.52) GAATSHRLMNAMEN1ALDH1A1
SCHEMBL24899757 0.74 HPGD (0.42) GAATSHRLMNAHPGDTPMT
SCHEMBL26699649 0.73 PSIP1 (0.45) CA1CA2
SCHEMBL24899829 0.73
SCHEMBL24899769 0.71 CYP1A2 (0.32) TSHRLMNAALDH1A1HPGDTPMT
SCHEMBL23057071 0.71 TDP1 (0.43) TSHRMEN1KMT2ACA1CA2
SCHEMBL29002222 0.70 ACHE (0.49) TSHRLMNAMEN1ALDH1A1KMT2A
SCHEMBL17288999 0.69 ALDH1A1 (0.41) TSHRLMNAMEN1ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023284869-A1 SULFUR/PHOSPHORUS-CONTAINING ARYL COMPOUND AND APPLICATION THEREOF 南京明德新药研发有限公司 2023-01-19 WO disclosed