Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSIP1 | O75475 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 6/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.39 |
| ▸ | ABAT | P80404 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28858779 | 0.79 | PSIP1 (0.42) | PSIP1HRH3LOXL2HDAC3HDAC6 | |
| SCHEMBL2033420 | 0.77 | GAA (0.40) | LOXL2CA1CA2CA12CA9 | |
| SCHEMBL18539752 | 0.77 | HRH3 (0.46) | PSIP1HRH3LOXL2HDAC3HDAC6 | |
| SCHEMBL26699652 | 0.77 | HRH3 (0.41) | PSIP1HRH3LOXL2HDAC3HDAC6 | |
| SCHEMBL28211613 | 0.75 | AOX1 (0.41) | PSIP1HRH3LOXL2HDAC3HDAC6 | |
| SCHEMBL27244263 | 0.74 | POLB (0.44) | PSIP1HRH3LOXL2HDAC3HDAC6 | |
| SCHEMBL24899753 | 0.73 | GAA (0.31) | CA1CA2 | |
| SCHEMBL19297523 | 0.73 | CYP2A6 (0.38) | HDAC3HDAC6NCOR2TAAR1KDM4E | |
| SCHEMBL13538144 | 0.73 | CA2 (0.48) | HRH3LOXL2HDAC3HDAC6NCOR2 | |
| SCHEMBL778908 | 0.72 | ALDH1A1 (0.52) | CA2CA4CA5AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023226950-A1 | PEPTIDOMIMETIC STAT PROTEIN DEGRADER, COMPOSITION AND USE THEREOF | 杭州和正医药有限公司 | 2023-11-30 | — | — | WO | disclosed |
| CN-117126231-A | Peptoid STAT protein degradation agent, composition and application thereof | 杭州和正医药有限公司 | 2023-11-28 | — | — | CN | disclosed |