Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 5/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.39 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.39 |
| ▸ | CETP | P11597 | 1/20 | 0.38 |
| ▸ | HNF4A | P41235 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 3/20 | 0.38 |
| ▸ | CTSB | P07858 | 3/20 | 0.38 |
| ▸ | CTSS | P25774 | 3/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.38 |
| ▸ | HTR3B | O95264 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.38 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24901420 | 0.87 | MAPT (0.43) | MAPTPOLBHTR6TSHRSERPINE1 | |
| SCHEMBL24901281 | 0.87 | ACACB (0.48) | MAPTPOLBALDH1A1KDM4E | |
| SCHEMBL24893377 | 0.85 | HTT (0.42) | MAPTHTR6USP2ALDH1A1TSHR | |
| SCHEMBL24901299 | 0.85 | KDM4E (0.49) | MAPTALDH1A1KDM4ESERPINE1HNF4A | |
| SCHEMBL24901428 | 0.76 | PRKDC (0.46) | MAPTALDH1A1KDM4E | |
| SCHEMBL24901336 | 0.76 | TERT (0.41) | MAPTPOLBALDH1A1KDM4E | |
| SCHEMBL13460198 | 0.74 | USP2 (0.47) | MAPTPOLBHTR6USP2ALDH1A1 | |
| SCHEMBL24893376 | 0.74 | HTT (0.55) | MAPTPOLBALDH1A1KDM4ESERPINE1 | |
| SCHEMBL24893490 | 0.74 | MMP13 (0.49) | — | |
| SCHEMBL24893399 | 0.73 | NPC1 (0.43) | HTR6ALDH1A1KDM4ESERPINE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4119138-A1 | DHODH INHIBITORS AND THEIR USE AS ANTIVIRAL AGENTS | Universität Hamburg (DE) | 2023-01-18 | — | — | EP | disclosed |