Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.48 |
| ▸ | TERT | O14746 | 1/20 | 0.45 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.44 |
| ▸ | ACLY | P53396 | 1/20 | 0.43 |
| ▸ | PRKDC | P78527 | 3/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.43 |
| ▸ | ALB | P02768 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMO | O15229 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24901428 | 0.88 | PRKDC (0.46) | ACACBTERTSLC16A3ACLYPRKDC | |
| SCHEMBL24901336 | 0.88 | TERT (0.41) | ACACBTERTSLC16A3ACLYPRKDC | |
| SCHEMBL24901420 | 0.88 | MAPT (0.43) | MAPTKMT2AGAARAB9ANPC1 | |
| SCHEMBL24901360 | 0.87 | MAPT (0.44) | MAPTKDM4EALDH1A1POLB | |
| SCHEMBL24901352 | 0.86 | MAPK10 (0.41) | ACACBTERTSLC16A3ACLYPRKDC | |
| SCHEMBL24901299 | 0.86 | KDM4E (0.49) | ACACBPIK3CAMAPTKDM4EALDH1A1 | |
| SCHEMBL24893418 | 0.85 | RAB9A (0.47) | ACACBTERTALBMAPTALDH1A1 | |
| SCHEMBL24893373 | 0.85 | TERT (0.46) | ACACBTERTSLC16A3ACLYPRKDC | |
| SCHEMBL24901393 | 0.84 | ADK (0.50) | PIK3CAMAPTALDH1A1KMO | |
| SCHEMBL24893490 | 0.84 | MMP13 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4119138-A1 | DHODH INHIBITORS AND THEIR USE AS ANTIVIRAL AGENTS | Universität Hamburg (DE) | 2023-01-18 | — | — | EP | disclosed |