Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 5/20 | 0.39 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HNF4A | P41235 | 1/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24901420 | 0.88 | MAPT (0.43) | SERPINE1MAPT | |
| SCHEMBL24893375 | 0.86 | KDM4E (0.44) | KDM4EALDH1A1FAAHSERPINE1MAPT | |
| SCHEMBL24901281 | 0.86 | ACACB (0.48) | KDM4EALDH1A1MAPTACACBPIK3CA | |
| SCHEMBL24901360 | 0.85 | MAPT (0.44) | KDM4EALDH1A1SERPINE1MAPTHNF4A | |
| SCHEMBL24901336 | 0.76 | TERT (0.41) | KDM4EALDH1A1MAPTACACBPIK3CA | |
| SCHEMBL24901428 | 0.76 | PRKDC (0.46) | KDM4EALDH1A1MAPTACACBPIK3CA | |
| SCHEMBL24893399 | 0.74 | NPC1 (0.43) | KDM4EALDH1A1SERPINE1 | |
| SCHEMBL24893490 | 0.73 | MMP13 (0.49) | — | |
| SCHEMBL24893376 | 0.73 | HTT (0.55) | KDM4EALDH1A1SERPINE1MAPTKEAP1 | |
| SCHEMBL24893418 | 0.72 | RAB9A (0.47) | ALDH1A1SERPINE1MAPTACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4119138-A1 | DHODH INHIBITORS AND THEIR USE AS ANTIVIRAL AGENTS | Universität Hamburg (DE) | 2023-01-18 | — | — | EP | disclosed |