Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | FBP1 | P09467 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | HBB | P68871 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2038046 | 0.85 | SMN1; SMN2 (0.39) | SMN1; SMN2MAPK1LMNAALOX15TSHR | |
| SCHEMBL29427162 | 0.80 | GPR3 (0.45) | SMN1; SMN2LMNAALOX15HAO1RAB9A | |
| SCHEMBL1221631 | 0.80 | GPR3 (0.45) | SMN1; SMN2LMNAALOX15HAO1RAB9A | |
| SCHEMBL25875499 | 0.76 | HAO1 (0.40) | SMN1; SMN2MAPK1LMNAALOX15TSHR | |
| SCHEMBL24901455 | 0.75 | HAO1 (0.35) | SMN1; SMN2MAPK1LMNAALOX15TSHR | |
| SCHEMBL30752460 | 0.74 | HAO1 (0.44) | SMN1; SMN2MAPK1LMNAALOX15TSHR | |
| SCHEMBL17442053 | 0.74 | POLB (0.35) | MAPK1LMNAKMT2AMEN1RAB9A | |
| SCHEMBL24901458 | 0.74 | FBP1 (0.46) | SMN1; SMN2MAPK1LMNAALOX15TSHR | |
| SCHEMBL29972693 | 0.72 | SMN1; SMN2 (0.47) | SMN1; SMN2MAPK1LMNAALOX15TSHR | |
| SCHEMBL2038048 | 0.72 | SMN1; SMN2 (0.47) | SMN1; SMN2MAPK1LMNAALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023286768-A1 | HYDROGENATED QUINOXALINES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2023-01-19 | — | — | WO | disclosed |