Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24901476 | 0.81 | MAPT (0.34) | MAPT | |
| SCHEMBL24901535 | 0.76 | MAPT (0.32) | MAPT | |
| SCHEMBL24901534 | 0.75 | ALDH1A1 (0.36) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL24901452 | 0.72 | ALDH1A1 (0.43) | KMT2AMEN1KDM4EALDH1A1MAPK1 | |
| SCHEMBL930657 | 0.71 | KDM4E (0.40) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL6684061 | 0.70 | MAPT (0.35) | MAPTKMT2A | |
| SCHEMBL24901470 | 0.70 | USP28 (0.38) | KMT2AMEN1KDM4EMAPK1 | |
| SCHEMBL9804244 | 0.67 | MAPT (0.34) | MAPT | |
| SCHEMBL7767195 | 0.67 | MAPT (0.41) | MAPTKMT2AMAPK1HTTNPSR1 | |
| SCHEMBL12144533 | 0.67 | MEN1 (0.43) | MAPTKMT2AMEN1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023286768-A1 | HYDROGENATED QUINOXALINES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2023-01-19 | — | — | WO | disclosed |