Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | FBP1 | P09467 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24901479 | 0.86 | GPR35 (0.38) | ALDH1A1CYP1A2NPSR1LMNACYP2C9 | |
| SCHEMBL23391511 | 0.81 | MAPT (0.37) | ALDH1A1NPSR1SMN1; SMN2POLBEPHX2 | |
| SCHEMBL1417843 | 0.78 | PPARA (0.47) | ALDH1A1CYP1A2NPSR1LMNACYP2C9 | |
| SCHEMBL24901468 | 0.76 | KMT2A (0.43) | ALDH1A1CYP1A2NPSR1LMNACYP2C9 | |
| SCHEMBL24901529 | 0.75 | MAPT (0.37) | ALDH1A1CYP1A2NPSR1KDM4EMEN1 | |
| SCHEMBL16744593 | 0.73 | LMNA (0.40) | ALDH1A1CYP1A2NPSR1LMNACYP2C9 | |
| SCHEMBL15226462 | 0.72 | EPHX2 (0.42) | ALDH1A1CYP1A2NPSR1SMN1; SMN2POLB | |
| SCHEMBL15897084 | 0.72 | EPHX2 (0.50) | ALDH1A1CYP1A2NPSR1LMNACYP2C9 | |
| SCHEMBL17713115 | 0.71 | NPSR1 (0.40) | ALDH1A1CYP1A2NPSR1LMNACYP2C9 | |
| SCHEMBL31466493 | 0.71 | NPSR1 (0.40) | ALDH1A1CYP1A2NPSR1LMNACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023286768-A1 | HYDROGENATED QUINOXALINES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2023-01-19 | — | — | WO | disclosed |