Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.52 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.50 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16248158 | 0.87 | L3MBTL1 (0.69) | SMN1; SMN2SMYD3L3MBTL1HDAC3NPC1 | |
| SCHEMBL12228078 | 0.86 | SMN1; SMN2 (0.57) | SMN1; SMN2SMYD3L3MBTL1HDAC3MRGPRX4 | |
| SCHEMBL9490800 | 0.86 | HDAC3 (0.66) | SMN1; SMN2SMYD3L3MBTL1HDAC3NPC1 | |
| SCHEMBL24527070 | 0.84 | HDAC3 (0.58) | SMN1; SMN2SMYD3L3MBTL1HDAC3MRGPRX4 | |
| SCHEMBL17303553 | 0.84 | SMN1; SMN2 (0.51) | SMN1; SMN2SMYD3L3MBTL1HDAC3NPC1 | |
| SCHEMBL12334128 | 0.84 | PARP1 (0.55) | SMN1; SMN2SMYD3L3MBTL1HDAC3NPC1 | |
| SCHEMBL9691071 | 0.83 | KAT6A (0.55) | SMN1; SMN2SMYD3L3MBTL1HDAC3MRGPRX4 | |
| SCHEMBL2056391 | 0.83 | HPGD (0.57) | SMN1; SMN2SMYD3L3MBTL1HDAC3MRGPRX4 | |
| SCHEMBL3195633 | 0.83 | LMNA (0.55) | SMN1; SMN2SMYD3L3MBTL1HDAC3NPC1 | |
| SCHEMBL15676745 | 0.83 | RAB9A (0.74) | SMN1; SMN2HDAC3NPC1RAB9AHDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230018460-A1 | 1-AMINOSULFONYL-2-CARBOXYPYRROLE DERIVATIVES AS METALLO-BETA-LACTAMASE INHIBITORS | Infex Therapeutics Limited (GB) | 2023-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230018460-A1 | 1-AMINOSULFONYL-2-CARBOXYPYRROLE DERIVATIVES AS METALLO-BETA-LACTAMASE INHIBITORS | CPN1, CMBL, ALDH7A1 | SMN1; SMN2 2657/4885SMYD3 807/4885L3MBTL1 1631/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.