SCHEMBL2490550

SCHEMBL2490550

OCCCC(O)C[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LGALS1 P09382 2/20 0.40
LGALS3 P17931 2/20 0.40
LGALS9 O00182 1/20 0.40
LGALS8 O00214 1/20 0.40
PPARG P37231 1/20 0.36
PPARD Q03181 1/20 0.36
PPARA Q07869 1/20 0.36
SELP P16109 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2493091 1.00 LGALS1 (0.40) LGALS1LGALS3LGALS9LGALS8PPARG
SCHEMBL25292780 1.00 LGALS1 (0.40) LGALS1LGALS3LGALS9LGALS8PPARG
SCHEMBL25290868 0.95 LGALS1 (0.39) LGALS1LGALS3LGALS9LGALS8PPARG
SCHEMBL2489714 0.95 LGALS1 (0.39) LGALS1LGALS3LGALS9LGALS8PPARG
SCHEMBL25291631 0.95 LGALS1 (0.39) LGALS1LGALS3LGALS9LGALS8PPARG
SCHEMBL2490527 0.95 LGALS1 (0.39) LGALS1LGALS3LGALS9LGALS8PPARG
SCHEMBL25292722 0.82 SELP (0.47) SELP
SCHEMBL2792360 0.82 SELP (0.47) SELP
SCHEMBL2793756 0.82 SELP (0.47) SELP
SCHEMBL25249456 0.82 SELP (0.47) SELP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7862804-B2 Admistration of C-glycoside compounds for depigmenting/whitening the skin LOREAL (FR) 2011-01-04 US claimed
EP-1774990-B1 Use of c-glycosides for depigmenting skin OREAL (FR) 2009-12-09 EP claimed
US-20070081956-A1 Admistration of C-glycoside compounds for depigmenting/whitening the skin L'OREAL (FR) 2007-04-12 US claimed
EP-2043594-B1 COSMETIC USE OF A C-GLYCOSIDE DERIVATIVE IN COMBINATION WITH ASCORBIC ACID L'ORÉAL (FR) 2017-03-15 EP disclosed
US-9421157-B2 Use of C-glycoside derivatives as pro-desquamating active agents L'OREAL (FR) 2016-08-23 US disclosed
WO-2013034855-A2 COMBINATION OF CARRAGEENAN AND C-GLYCOSIDE AND USES THEREOF L'OREAL (FR) 2013-03-14 WO disclosed
EP-2379050-A2 PRODUCT FOR PREVENTING OR TREATING HAIR GREYING L'Oréal (FR) 2011-10-26 EP disclosed
US-7862804-B2 Admistration of C-glycoside compounds for depigmenting/whitening the skin LOREAL (FR) 2011-01-04 US disclosed
US-20100190742-A1 COSMETIC/PHARMACEUTICAL COMPOSITIONS COMPRISING HYALURONIC ACID AND ADMINISTRATION THEREOF FOR REDUCING SIGNS OF AGING L'OREAL (FR) 2010-07-29 US disclosed
WO-2010082001-A2 PRODUCT FOR PREVENTING OR TREATING HAIR GREYING L'OREAL (FR) 2010-07-22 WO disclosed
US-20100112100-A1 COMPOSITIONS COMPRISING A C-GLYCOSIDE COMPOUND L'OREAL (FR) 2010-05-06 US disclosed
WO-2008004165-A2 USE OF C-GLYCOSIDE DERIVATIVES AS PRO-DESQUAMATING ACTIVE AGENTS L'OREAL (FR) 2008-01-10 WO disclosed
US-20080008673-A1 Compositions comprising at least one C-glycoside derivative L'OREAL S.A. (FR) 2008-01-10 US disclosed
US-20080008674-A1 Use of C-glycoside derivative for improving the skin's barrier function L'OREAL (FR) 2008-01-10 US disclosed
WO-2008004164-A2 COSMETIC AND/OR DERMATOLOGICAL COMPOSITION COMBINING A C-GLYCOSIDE DERIVATIVE AND A DESQUAMATING AGENT L'OREAL (FR) 2008-01-10 WO disclosed
EP-1875893-A2 Composition combining a C-glycoside derivative with an associative polymer L'OREAL (FR) 2008-01-09 EP disclosed
EP-1875894-A2 Use of at least one C-glycoside derivative as a soothing agent L'OREAL (FR) 2008-01-09 EP disclosed
US-20080003191-A1 Composition combining a C-glycoside derivative and an emulsifying polymer L'OREAL (FR) 2008-01-03 US disclosed
EP-1774990-A1 Use of c-glycosides for depigmenting skin L'Oréal (FR) 2007-04-18 EP disclosed
US-20070081956-A1 Admistration of C-glycoside compounds for depigmenting/whitening the skin L'OREAL (FR) 2007-04-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080008673-A1 Compositions comprising at least one C-glycoside derivative DSG1, TYR, CUTA LGALS1 129/4885LGALS3 100/4885LGALS9 469/4885
US-20070081956-A1 Admistration of C-glycoside compounds for depigmenting/whitening the skin TYR, CAT, NQO1 LGALS1 640/4885LGALS3 554/4885LGALS9 1197/4885
US-20100190742-A1 COSMETIC/PHARMACEUTICAL COMPOSITIONS COMPRISING HYALURONIC ACID AND ADMINISTRATION THEREOF FOR REDUCING SIGNS OF AGING GLA, CD44, FUT6 LGALS1 88/4885LGALS3 81/4885LGALS9 235/4885
US-20100112100-A1 COMPOSITIONS COMPRISING A C-GLYCOSIDE COMPOUND UGCG, GANC, CUTA LGALS1 187/4885LGALS3 146/4885LGALS9 263/4885
US-20080008674-A1 Use of C-glycoside derivative for improving the skin's barrier function CUTA, UGCG, GLA LGALS1 29/4885LGALS3 20/4885LGALS9 35/4885
US-20080003191-A1 Composition combining a C-glycoside derivative and an emulsifying polymer CUTA, UGCG, PSAP LGALS1 154/4885LGALS3 98/4885LGALS9 431/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.