Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7696948 | 0.85 | ALDH1A1 (0.54) | TAAR1AKR1B1ALDH1A1HPGDTDP1 | |
| SCHEMBL8042811 | 0.85 | TAAR1 (0.55) | TAAR1HPGDTDP1MAPTSMN1; SMN2 | |
| SCHEMBL5274928 | 0.85 | TSHR (0.45) | TAAR1AKR1B1ALDH1A1HPGDTDP1 | |
| SCHEMBL15106903 | 0.80 | CYP2A6 (0.50) | TAAR1AKR1B1ALDH1A1SMN1; SMN2GABRA1 | |
| SCHEMBL10930849 | 0.80 | HPGD (0.46) | AKR1B1ALDH1A1HPGDTDP1MAPT | |
| SCHEMBL5830293 | 0.79 | TSHR (0.52) | AKR1B1ALDH1A1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL10365089 | 0.79 | GABRA1 (0.41) | TAAR1AKR1B1ALDH1A1HPGDTDP1 | |
| SCHEMBL9792845 | 0.78 | CYP3A4 (0.32) | ALDH1A1HPGDTDP1MAPTSMN1; SMN2 | |
| SCHEMBL11500020 | 0.78 | DPP4 (0.63) | ALDH1A1TDP1MAPTKMT2ALMNA | |
| SCHEMBL10325016 | 0.76 | TAAR1 (0.52) | TAAR1AKR1B1ALDH1A1HPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0253396-B1 | PROCESS FOR PREPARING 5,6-SUBSTITUTED-2,4-QUINAZOLINEDIAMINES AND INTERMEDIATES | WARNER-LAMBERT COMPANY (US) | 1993-03-17 | — | — | EP | claimed |
| EP-0253396-A2 | Process for preparing 5,6-substituted-2,4-quinazolinediamines and intermediates | WARNER-LAMBERT COMPANY (US) | 1988-01-20 | — | — | EP | claimed |
| CN-109939092-B | Phenyl carbamate compounds for use in preventing or treating pediatric epilepsy and epilepsy-related syndrome | 比皮艾思药物研发有限公司 | 2022-03-22 | — | — | CN | disclosed |
| CN-105188690-B | Phenyl carbamate compounds for use in preventing or treating movement disorders | 比皮艾思药物研发有限公司 | 2020-06-12 | — | — | CN | disclosed |
| CN-105188689-B | Phenyl carbamate compounds for use in preventing or treating epilepsy and epilepsy-related syndromes | 比皮艾思药物研发有限公司 | 2020-04-10 | — | — | CN | disclosed |
| CN-110478343-A | Phenyl carbamate compound and comprising the compound for preventing or treating the composition of disease caused by nerve gas | BIO PHARM SOLUTIONS CO LTD | 2019-11-22 | — | — | CN | disclosed |
| CN-105189450-B | Phenyl carbamate compound and composition for preventing or treating mental disorder comprising the same | 比皮艾思药物研发有限公司 | 2019-09-13 | — | — | CN | disclosed |
| CN-105209430-B | Phenyl carbamate compounds and neuroprotective compositions comprising the same | 比皮艾思药物研发有限公司 | 2019-09-13 | — | — | CN | disclosed |
| CN-109939092-A | For preventing or treating the carbanilate compound of children epilepsy and epilepsy related syndromes | 比皮艾思药物研发有限公司 | 2019-06-28 | — | — | CN | disclosed |
| CN-105388281-B | Detect enzyme linked immunological kit and its application of iprodione | 中国烟草总公司郑州烟草研究院 | 2017-09-12 | — | — | CN | disclosed |
| CN-105388286-B | A kind of test strips for detecting iprodione and its preparation method and application | 中国烟草总公司郑州烟草研究院 | 2017-07-07 | — | — | CN | disclosed |
| WO-2012002773-A2 | PHENYLCARBAMATE COMPOUND AND MUSCLE RELAXANT CONTAINING THE SAME | BIO-PHARM SOLUTIONS CO., LTD. (KR) | 2012-01-05 | — | — | WO | disclosed |
| EP-1246815-B1 | PHENYLPIPERAZINYL DERIVATIVES | LUNDBECK & CO AS H (DK) | 2004-03-17 | — | — | EP | disclosed |
| US-20030083336-A1 | Phenylpiperazinyl derivatives | H. LUNDBECK A/S (DK) | 2003-05-01 | — | — | US | disclosed |
| EP-1246815-A1 | PHENYLPIPERAZINYL DERIVATIVES | H. Lundbeck A/S (DK) | 2002-10-09 | — | — | EP | disclosed |
| WO-2001049677-A1 | PHENYLPIPERAZINYL DERIVATIVES | H. LUNDBECK A/S (DK) | 2001-07-12 | — | — | WO | disclosed |
| EP-0253396-B1 | PROCESS FOR PREPARING 5,6-SUBSTITUTED-2,4-QUINAZOLINEDIAMINES AND INTERMEDIATES | WARNER-LAMBERT COMPANY (US) | 1993-03-17 | — | — | EP | disclosed |
| EP-0253396-A2 | Process for preparing 5,6-substituted-2,4-quinazolinediamines and intermediates | WARNER-LAMBERT COMPANY (US) | 1988-01-20 | — | — | EP | disclosed |
| US-4677219-A | Substituted benzonitriles | WARNER-LAMBERT COMPANY (US) | 1987-06-30 | — | — | US | disclosed |
| US-4560814-A | Process for alkylating halogenated and trifluoromethylated benzene compounds | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1985-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030083336-A1 | Phenylpiperazinyl derivatives | DRD4, DRD2, DRD3 | TAAR1 101/4885AKR1B1 1515/4885ALDH1A1 840/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.