SCHEMBL7696948

SCHEMBL7696948

C=CCc1c(Cl)cccc1C=C

nearest known ligand 0.54

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.54
MAPT P10636 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
TAAR1 Q96RJ0 2/20 0.38
HPGD P15428 2/20 0.36
AKR1B1 P15121 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
GABRA1 P14867 1/20 0.33
GABRB2 P47870 1/20 0.33
GSR P00390 1/20 0.33
ADRA2A P08913 1/20 0.33
ADRA2B P18089 1/20 0.33
ADRA2C P18825 1/20 0.33
TRPA1 O75762 1/20 0.32
CYP1A2 P05177 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL249069 0.85 TAAR1 (0.44) ALDH1A1MAPTTDP1TAAR1HPGD
SCHEMBL1486001 0.80 ALDH1A1 (0.54) ALDH1A1TDP1TAAR1HPGDAKR1B1
SCHEMBL10403429 0.80 ALDH1A1 (0.54) ALDH1A1MAPTTAAR1HPGDAKR1B1
SCHEMBL7219053 0.78 GABRA1 (0.47) ALDH1A1MAPTAKR1B1GABRA1GABRB2
SCHEMBL9310723 0.77 ALDH1A1 (0.50) ALDH1A1TAAR1HPGDAKR1B1SMN1; SMN2
SCHEMBL5409813 0.76 GABRA1 (0.41) ALDH1A1MAPTHPGDAKR1B1RAB9A
SCHEMBL21987780 0.76 IMPDH2 (0.40) ALDH1A1TDP1HPGDGABRA1GABRB2
SCHEMBL7731174 0.76 MAPT (0.35) ALDH1A1MAPTGABRA1GABRB2
SCHEMBL6470785 0.76 ALDH1A1 (0.37) ALDH1A1HPGDSMN1; SMN2GABRA1GABRB2
SCHEMBL14402953 0.76 ALDH1A1 (0.34) ALDH1A1GABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6353070-B1 STAR POLYMER OBTAINED BY POLYMERIZING VINYLAROMATIC MONOMER AND BRANCHING MONOMER CONTAINING AT LEAST TWO VINYLAROMATIC RADICALS IN PRESENCE OF CATALYST COMPRISING TRANSITION METAL COMPLEX, CATION-FORMING AGENT, OPTIONAL ALUMINUM COMPOUND BASF AKTIENGESELLSCHAFT (DE) 2002-03-05 US disclosed
US-6303806-B2 TITANIUM COMPOUNDS AS BRANCHING MONOMER UNITS BASF AKTIENGESELLSCHAFT (DE) 2001-10-16 US disclosed
US-20010009966-A1 Star polymers, and their preparation WUNSCH JOSEF (DE) 2001-07-26 US disclosed
US-6235838-B1 USING STYRENE/DIPHENYLETHYLENE-DIENE BLOCK COPOLYMERS AS DISPERSING AUXILIARIES. BASF AKTIENGESELLSCHAFT (DE) 2001-05-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010009966-A1 Star polymers, and their preparation MYB, PICALM, VMA21 ALDH1A1 4099/4885MAPT 2152/4885TDP1 3299/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.