SCHEMBL2490791

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2489523	0.81	ESR1 (0.41)	ESR1ESR2HPGDCYP3A4LMNA
	SCHEMBL2488565	0.80	ADRB1 (0.52)	HTR5AHPGDCYP3A4TSHRHTR6
	SCHEMBL2492360	0.79	ALDH1A1 (0.44)	ESR1ESR2HPGDCYP3A4LMNA
	SCHEMBL569963	0.79	SIGMAR1 (0.48)	HTR5AHPGDLMNATSHRHTR6
	SCHEMBL9090858	0.78	SIGMAR1 (0.47)	HTR5AHPGDLMNATSHRHTR6
	SCHEMBL8411629	0.78	SIGMAR1 (0.47)	HTR5AHPGDLMNATSHRHTR6
	SCHEMBL2494068	0.76	HTR3A (0.56)	HTR6ADRB1
	SCHEMBL2495637	0.74	ESR1 (0.53)	ESR1ESR2HPGDCYP3A4LMNA
	SCHEMBL27544718	0.73	ESR1 (0.52)	ESR1ESR2HPGDCYP3A4LMNA
	Succinic Acid SCHEMBL19644019	0.72	SIGMAR1 (0.44)	CYP3A4TSHRHSD17B10OPRD1CHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.