SCHEMBL24908327

SCHEMBL24908327

Bc1c(B)c(B)c2c(-c3ccc4oc5cc6ccccc6cc5c4c3)c3c(B)c(B)c(B)c(B)c3c(-c3ccc(-c4ccc5c(ccc6ccccc65)c4)cc3)c2c1B

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.36
MAPT P10636 5/20 0.36
HSD17B10 Q99714 3/20 0.36
HPGD P15428 3/20 0.36
TSHR P16473 2/20 0.36
GLA P06280 2/20 0.36
HTT P42858 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
MAOB P27338 1/20 0.36
ALDH1A1 P00352 8/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
ESR1 P03372 2/20 0.35
POLB P06746 1/20 0.35
HNF4A P41235 1/20 0.35
ALOX15 P16050 1/20 0.35
CASP1 P29466 1/20 0.35
CASP7 P55210 1/20 0.35
CYP1B1 Q16678 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24908177 1.00 KDM4E (0.36) KDM4EMAPTHSD17B10HPGDTSHR
SCHEMBL24908221 0.95 KDM4E (0.37) KDM4EMAPTHSD17B10HPGDTSHR
SCHEMBL24766815 0.94 KDM4E (0.37) KDM4EMAPTHSD17B10HPGDTSHR
SCHEMBL24908172 0.94 PGR (0.38) KDM4EMAPTHSD17B10HPGDTSHR
SCHEMBL25006246 0.93 KDM4E (0.37) KDM4EMAPTHSD17B10HPGDTSHR
SCHEMBL25006045 0.93 KDM4E (0.37) KDM4EMAPTHSD17B10HPGDTSHR
SCHEMBL29332371 0.93 ESR1 (0.36) KDM4EMAPTHSD17B10HPGDTSHR
SCHEMBL26517424 0.91 KDM4E (0.40) KDM4EMAPTHSD17B10HPGDTSHR
SCHEMBL24908333 0.89 ALDH1A1 (0.38) KDM4EMAPTHSD17B10HPGDTSHR
SCHEMBL24908243 0.88 CYP1A1 (0.38) KDM4EMAPTHSD17B10HPGDTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230047477-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO.,LTD. (JP) 2023-02-16 US disclosed
US-20230042023-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO.,LTD. (JP) 2023-02-09 US disclosed
US-20230020436-A1 NOVEL COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO.,LTD. (JP) 2023-01-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230020436-A1 NOVEL COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS MRPS22, RER1, EMC2 KDM4E 2476/4885MAPT 3554/4885HSD17B10 3136/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.