SCHEMBL24908690

SCHEMBL24908690

O=C(Nc1ccccc1)C(c1ccc2oc3ccccc3c2c1)N1C(=O)c2cc(Oc3ccccc3)c3c4c(Oc5ccccc5)cc5c6c(cc(Oc7ccccc7)c(c7c(Oc8ccccc8)cc(c2c37)C1=O)c64)C(=O)N(C(C(=O)Nc1ccccc1)c1ccc2oc3ccccc3c2c1)C5=O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.40
MEN1 O00255 7/20 0.40
KMT2A Q03164 7/20 0.40
HPGD P15428 5/20 0.40
SMN1; SMN2 Q16637 4/20 0.40
KDM4E B2RXH2 3/20 0.40
ALDH1A1 P00352 3/20 0.40
POLB P06746 2/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
HTT P42858 1/20 0.40
NPY5R Q15761 1/20 0.36
NPC1 O15118 3/20 0.36
RAB9A P51151 3/20 0.36
GAA P10253 2/20 0.36
PTGS2 P35354 2/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
LMNA P02545 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24909171 0.84 ALOX15 (0.39) MAPTMEN1KMT2AHPGDSMN1; SMN2
SCHEMBL24704752 0.84 MAPT (0.37) MAPTMEN1KMT2AHPGDSMN1; SMN2
SCHEMBL24909237 0.83 KMT2A (0.36) MAPTMEN1KMT2AHPGDSMN1; SMN2
SCHEMBL24704748 0.80 MAPT (0.36) MAPTMEN1KMT2AHPGDSMN1; SMN2
SCHEMBL24704835 0.78 MAPT (0.33) MAPTMEN1KMT2AHPGDSMN1; SMN2
SCHEMBL24908980 0.78 PTGS2 (0.36) MAPTMEN1KMT2AHPGDSMN1; SMN2
SCHEMBL24908724 0.76 ALDH1A1 (0.33) MAPTKMT2AHPGDSMN1; SMN2KDM4E
SCHEMBL24705280 0.74 THRB (0.39) MAPTSMN1; SMN2ALDH1A1HTTNPY5R
SCHEMBL24909069 0.73 TP53 (0.40) MAPTMEN1KMT2ASMN1; SMN2ALDH1A1
SCHEMBL24909234 0.73 ALDH1A1 (0.42) MAPTMEN1KMT2ASMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230023648-A1 COMPOUND, PHOTOSENSITIVE FLUORESCENT RESIN COMPOSITION COMPRISING SAME, COLOR CONVERSION FILM PREPARED USING SAME, BACKLIGHT UNIT, AND DISPLAY DEVICE LG CHEM, LTD (KR) 2023-01-26 US disclosed