SCHEMBL24908696

SCHEMBL24908696

Cc1cccc(-c2cccc(Oc3cc4c5c(cc(Oc6cccc(-c7cccc(C)c7)c6)c6c7c(Oc8cccc(-c9cccc(C)c9)c8)cc8c9c(cc(Oc%10cccc(-c%11cccc(C)c%11)c%10)c(c3c56)c97)C(=O)N(C(C(=O)NC(C(F)(F)F)C(F)(F)F)c3ccccc3)C8=O)C(=O)N(C(C(=O)NC(C(F)(F)F)C(F)(F)F)c3ccccc3)C4=O)c2)c1

nearest known ligand 0.35

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 2/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
GAA P10253 1/20 0.35
MAPK1 P28482 1/20 0.34
HCRTR1 O43613 1/20 0.33
HCRTR2 O43614 1/20 0.33
CASP1 P29466 1/20 0.32
HSD17B2 P37059 1/20 0.31
CMA1 P23946 1/20 0.31
CTRC Q99895 1/20 0.31
ADORA3 P0DMS8 2/20 0.31
ADORA2A P29274 2/20 0.31
LMNA P02545 1/20 0.31
THRB P10828 1/20 0.31
PPARG P37231 1/20 0.31
PPARA Q07869 1/20 0.31
POLB P06746 1/20 0.31
SLC6A9 P48067 1/20 0.30
PTPN5 P54829 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24909082 0.89 LMNA (0.32) LMNA
SCHEMBL24908740 0.81 ALDH1A1 (0.39) GAACASP1LMNA
SCHEMBL24908687 0.79 LMNA (0.33) NPSR1MAPK1LMNA
SCHEMBL24909095 0.78 POLB (0.40) L3MBTL1MAPK1LMNAPOLB
SCHEMBL24909279 0.73 KMT2A (0.40) L3MBTL1GAAMAPK1CASP1THRB
SCHEMBL24909121 0.71 PTPN1 (0.36)
SCHEMBL24908945 0.69 TNF (0.39) L3MBTL1MAPK1LMNAPOLB
SCHEMBL24909069 0.68 TP53 (0.40) NPSR1L3MBTL1MAPK1LMNATHRB
SCHEMBL24908683 0.68 THRB (0.37) L3MBTL1CASP1LMNATHRBPOLB
SCHEMBL24908682 0.68 TP53 (0.34) NPSR1GAALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230023648-A1 COMPOUND, PHOTOSENSITIVE FLUORESCENT RESIN COMPOSITION COMPRISING SAME, COLOR CONVERSION FILM PREPARED USING SAME, BACKLIGHT UNIT, AND DISPLAY DEVICE LG CHEM, LTD (KR) 2023-01-26 US disclosed