SCHEMBL24909255

SCHEMBL24909255

Cc1cccc(OC(=O)C(CC(F)(F)F)N2C(=O)c3cc(Oc4ccc(C(C)C)cc4)c4c5c(Oc6ccc(C(C)C)cc6)cc6c7c(cc(Oc8ccc(C(C)C)cc8)c(c8c(Oc9ccc(C(C)C)cc9)cc(c3c48)C2=O)c75)C(=O)N(C(CC(F)(F)F)C(=O)Oc2cccc(C)c2)C6=O)c1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.34
MEN1 O00255 2/20 0.34
KDM4E B2RXH2 2/20 0.34
CRHBP P24387 1/20 0.34
CRHR2 Q13324 1/20 0.34
LMNA P02545 6/20 0.33
SMN1; SMN2 Q16637 4/20 0.33
MAPT P10636 3/20 0.33
HTT P42858 1/20 0.33
ALDH1A1 P00352 4/20 0.33
HPGD P15428 2/20 0.33
GLA P06280 1/20 0.33
L3MBTL1 Q9Y468 2/20 0.32
KLK7 P49862 1/20 0.32
MCL1 Q07820 1/20 0.32
APEX1 P27695 1/20 0.32
HCAR2 Q8TDS4 1/20 0.31
CHRM5 P08912 1/20 0.31
POLB P06746 1/20 0.31
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24705104 0.79 DNMT1 (0.34) KMT2AMEN1KDM4ELMNASMN1; SMN2
SCHEMBL24705102 0.79 DNMT1 (0.33) KMT2AMEN1LMNASMN1; SMN2MAPT
SCHEMBL24909057 0.79 KMT2A (0.48) KMT2AMEN1KDM4ELMNASMN1; SMN2
SCHEMBL24909053 0.76 POLB (0.33) KMT2AMEN1KDM4ESMN1; SMN2ALDH1A1
SCHEMBL24909006 0.76 SMN1; SMN2 (0.34) LMNASMN1; SMN2
SCHEMBL24909194 0.76 MGLL (0.37) KMT2AKDM4EALDH1A1HPGDGLA
SCHEMBL24908737 0.75 ALDH1A1 (0.35) KDM4ELMNASMN1; SMN2MAPTALDH1A1
SCHEMBL24705830 0.74 KDM4E (0.40) KMT2AMEN1KDM4ELMNAMAPT
SCHEMBL24704893 0.74 HSD11B1 (0.32) KDM4EALDH1A1HPGDGLA
SCHEMBL24909083 0.74 ALDH1A1 (0.39) KMT2AMEN1KDM4ECRHBPCRHR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230023648-A1 COMPOUND, PHOTOSENSITIVE FLUORESCENT RESIN COMPOSITION COMPRISING SAME, COLOR CONVERSION FILM PREPARED USING SAME, BACKLIGHT UNIT, AND DISPLAY DEVICE LG CHEM, LTD (KR) 2023-01-26 US disclosed