Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | MGAM | O43451 | 1/20 | 0.56 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | SI | P14410 | 1/20 | 0.56 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.56 |
| ▸ | SLC9A1 | P19634 | 5/20 | 0.54 |
| ▸ | GRM2 | Q14416 | 5/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9618157 | 0.92 | RPS6KA3 (0.84) | RPS6KA3TDP1NPC1RAB9ASLC9A1 | |
| SCHEMBL2494163 | 0.87 | RPS6KA3 (0.77) | RPS6KA3TDP1NPC1RAB9AMGAM | |
| SCHEMBL3342201 | 0.84 | RPS6KA3 (0.73) | RPS6KA3NPC1RAB9AMGAMAMY1A | |
| SCHEMBL22375107 | 0.84 | RPS6KA3 (1.00) | RPS6KA3NPC1RAB9AMGAMAMY1A | |
| SCHEMBL2494276 | 0.84 | RPS6KA3 (0.59) | RPS6KA3TDP1NPC1RAB9AMGAM | |
| SCHEMBL31267895 | 0.81 | RPS6KA3 (0.68) | RPS6KA3NPC1RAB9AMGAMAMY1A | |
| SCHEMBL2491190 | 0.81 | RPS6KA3 (0.68) | RPS6KA3NPC1RAB9AMGAMAMY1A | |
| SCHEMBL7813053 | 0.80 | RPS6KA3 (0.70) | RPS6KA3NPC1RAB9AMGAMAMY1A | |
| SCHEMBL2490331 | 0.78 | RPS6KA3 (0.60) | RPS6KA3TDP1NPC1RAB9AMGAM | |
| SCHEMBL3403852 | 0.78 | SLC9A1 (0.63) | RPS6KA3TDP1NPC1RAB9AMGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102688233-B | Benzotriazole Derivative is as the synthesis of RSK2 inhibitor and application | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2016-02-17 | — | — | CN | disclosed |
| US-8330039-B2 | Solar cell modules with poly(vinyl butyral) encapsulant comprising unsaturated heterocyclic compound | E I DU PONT DE NEMOURS AND COMPANY (US) | 2012-12-11 | — | — | US | disclosed |
| CN-102688233-A | Synthesis of benzotriazol derivative as RSK2 inhibitor and application thereof | UNIV EAST CHINA SCIENCE & TECH | 2012-09-26 | — | — | CN | disclosed |
| EP-2380208-A1 | SOLAR CELL MODULES WITH POLY(VINYL BUTYRAL) ENCAPSULANT COMPRISING UNSATURATED HETEROCYCLIC COMPOUND | E. I. du Pont de Nemours and Company (US) | 2011-10-26 | — | — | EP | disclosed |
| WO-2010085664-A1 | SOLAR CELL MODULES WITH POLY(VINYL BUTYRAL) ENCAPSULANT COMPRISING UNSATURATED HETEROCYCLIC COMPOUND | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-07-29 | — | — | WO | disclosed |
| US-20100180947-A1 | SOLAR CELL MODULES WITH POLY(VINYL BUTYRAL) ENCAPSULANT COMPRISING UNSATURATED HETEROCYCLIC COMPOUND | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-07-22 | — | — | US | disclosed |