Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA3 | P51812 | 1/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | SLC9A1 | P19634 | 5/20 | 0.51 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.49 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | MGAM | O43451 | 2/20 | 0.47 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.47 |
| ▸ | SI | P14410 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9618157 | 0.92 | RPS6KA3 (0.84) | RPS6KA3CYP2C9CYP2C19CYP1A2ALDH1A1 | |
| SCHEMBL2494163 | 0.87 | RPS6KA3 (0.77) | RPS6KA3CYP2C9CYP2C19CYP1A2ALDH1A1 | |
| SCHEMBL3342201 | 0.84 | RPS6KA3 (0.73) | RPS6KA3CYP2C9CYP2C19CYP1A2ALDH1A1 | |
| SCHEMBL2490946 | 0.84 | RPS6KA3 (0.73) | RPS6KA3CYP2C9CYP2C19CYP1A2ALDH1A1 | |
| SCHEMBL7813053 | 0.82 | RPS6KA3 (0.70) | RPS6KA3ALDH1A1POLBRAB9ANPC1 | |
| SCHEMBL31267895 | 0.81 | RPS6KA3 (0.68) | RPS6KA3CYP2C9CYP2C19CYP1A2ALDH1A1 | |
| SCHEMBL2491190 | 0.81 | RPS6KA3 (0.68) | RPS6KA3CYP2C9CYP2C19CYP1A2ALDH1A1 | |
| SCHEMBL5550585 | 0.78 | RPS6KA3 (0.64) | RPS6KA3CYP2C9CYP2C19CYP1A2ALDH1A1 | |
| SCHEMBL3403852 | 0.78 | SLC9A1 (0.63) | RPS6KA3CYP2C9CYP2C19CYP1A2ALDH1A1 | |
| SCHEMBL16398499 | 0.78 | GRM2 (0.75) | RPS6KA3SLC9A1KCNMA1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200268897-A1 | Phosphatase Binding Compounds and Methods of Using Same | YALE UNIVERSITY | 2020-08-27 | — | — | US | disclosed |
| CN-102688233-B | Benzotriazole Derivative is as the synthesis of RSK2 inhibitor and application | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2016-02-17 | — | — | CN | disclosed |
| CN-102688233-A | Synthesis of benzotriazol derivative as RSK2 inhibitor and application thereof | UNIV EAST CHINA SCIENCE & TECH | 2012-09-26 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200268897-A1 | Phosphatase Binding Compounds and Methods of Using Same | PPP5C, PPP4C, DUSP26 | RPS6KA3 675/4885CYP2C9 4854/4885CYP2C19 4878/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.