Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.70 |
| ▸ | RAB9A | P51151 | 10/20 | 0.56 |
| ▸ | MGAM | O43451 | 5/20 | 0.56 |
| ▸ | AMY1A | P0DUB6 | 5/20 | 0.56 |
| ▸ | GAA | P10253 | 5/20 | 0.56 |
| ▸ | SI | P14410 | 5/20 | 0.56 |
| ▸ | MGAM2 | Q2M2H8 | 5/20 | 0.56 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 7/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.51 |
| ▸ | APAF1 | O14727 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | TDP2 | O95551 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9618157 | 0.87 | RPS6KA3 (0.84) | RPS6KA3RAB9AEGLN3NPC1MAPT | |
| SCHEMBL2494163 | 0.85 | RPS6KA3 (0.77) | RPS6KA3RAB9AMGAMAMY1AGAA | |
| SCHEMBL22375107 | 0.82 | RPS6KA3 (1.00) | RPS6KA3RAB9AMGAMAMY1AGAA | |
| SCHEMBL23824722 | 0.82 | HCAR3 (0.53) | RPS6KA3RAB9AMGAMAMY1AGAA | |
| SCHEMBL9091451 | 0.81 | RAB9A (0.50) | RPS6KA3RAB9AMGAMAMY1AGAA | |
| SCHEMBL2490946 | 0.80 | RPS6KA3 (0.73) | RPS6KA3RAB9AMGAMAMY1AGAA | |
| SCHEMBL3342201 | 0.80 | RPS6KA3 (0.73) | RPS6KA3RAB9AMGAMAMY1AGAA | |
| SCHEMBL23066417 | 0.78 | EGLN3 (0.60) | RPS6KA3RAB9AMGAMAMY1AGAA | |
| SCHEMBL438390 | 0.77 | MGAM (0.62) | RPS6KA3RAB9AMGAMAMY1AGAA | |
| SCHEMBL27890010 | 0.77 | RPS6KA3 (0.64) | RPS6KA3MGAMAMY1AGAASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |