SCHEMBL3342201

SCHEMBL3342201

Cc1ccc(NCn2nnc3ccccc32)cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ RPS6KA3 P51812 1/20 0.73
▸ RAB9A P51151 6/20 0.63
▸ NPC1 O15118 4/20 0.63
▸ CYP1A2 P05177 2/20 0.60
▸ CYP2C9 P11712 2/20 0.60
▸ CYP2C19 P33261 2/20 0.60
▸ POLB P06746 2/20 0.60
▸ SMN1; SMN2 Q16637 3/20 0.60
▸ KMT2A Q03164 2/20 0.60
▸ LMNA P02545 1/20 0.60
▸ ALDH1A1 P00352 3/20 0.59
▸ MGAM O43451 1/20 0.56
▸ AMY1A P0DUB6 1/20 0.56
▸ GAA P10253 1/20 0.56
▸ SI P14410 1/20 0.56
▸ MGAM2 Q2M2H8 1/20 0.56
▸ SLC9A1 P19634 7/20 0.56
▸ TP53 P04637 1/20 0.50
▸ ALOX15 P16050 1/20 0.50
▸ NFKB1 P19838 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9618157 0.92 RPS6KA3 (0.84) RPS6KA3RAB9ANPC1CYP1A2CYP2C9
SCHEMBL2494163 0.87 RPS6KA3 (0.77) RPS6KA3RAB9ANPC1CYP1A2CYP2C9
SCHEMBL22375107 0.84 RPS6KA3 (1.00) RPS6KA3RAB9ANPC1CYP1A2CYP2C9
SCHEMBL2490946 0.84 RPS6KA3 (0.73) RPS6KA3RAB9ANPC1CYP1A2CYP2C9
SCHEMBL31267895 0.84 RPS6KA3 (0.68) RPS6KA3RAB9ANPC1CYP1A2CYP2C9
SCHEMBL2488109 0.84 RAB9A (0.65) RPS6KA3RAB9ANPC1CYP1A2CYP2C9
SCHEMBL2491190 0.84 RPS6KA3 (0.68) RPS6KA3RAB9ANPC1CYP1A2CYP2C9
SCHEMBL10903221 0.82 CYP1A2 (0.54) RPS6KA3RAB9ANPC1CYP1A2CYP2C9
SCHEMBL2491842 0.80 GAA (0.63) RPS6KA3RAB9ANPC1CYP1A2CYP2C9
SCHEMBL7813053 0.80 RPS6KA3 (0.70) RPS6KA3RAB9ANPC1POLBSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4689028-A1 LUBRICANT ADDITIVE COMPOSITION FOR ELECTRIC VEHICLE The Lubrizol Corporation (US) 2026-02-11 — — EP disclosed
WO-2025216922-A1 BORON CONTAINING AUTOMOTIVE GEAR OIL THE LUBRIZOL CORPORATION (US) 2025-10-16 — — WO disclosed
WO-2024206581-A1 LUBRICANT ADDITIVE COMPOSITION FOR ELECTRIC VEHICLE THE LUBRIZOL CORPORATION (US) 2024-10-03 — — WO disclosed
US-20150045263-A1 Lubricating Composition LUBRIZOL CORP (US) 2015-02-12 — — US disclosed
US-20100160191-A1 Lubricating Composition THE LUBRIZOL CORPORATION (US) 2010-06-24 — — US disclosed
US-20090093384-A1 Lubricants That Decrease Micropitting for Industrial Gears THE LUBRIZOL CORPORATION (US) 2009-04-09 — — US disclosed
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