Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1902531 | 1.00 | HPGD (0.43) | HPGDALDH1A1PTGDR2MTNR1AMTNR1B | |
| SCHEMBL2492234 | 0.94 | RAB9A (0.44) | HPGDALDH1A1PTGDR2MTNR1AMTNR1B | |
| SCHEMBL1900071 | 0.94 | RAB9A (0.44) | HPGDALDH1A1PTGDR2MTNR1AMTNR1B | |
| SCHEMBL1902893 | 0.93 | MEN1 (0.43) | HPGDALDH1A1PTGDR2MTNR1AMTNR1B | |
| SCHEMBL1902210 | 0.89 | CYP1A2 (0.45) | PTGDR2MTNR1AMTNR1BNPC1RAB9A | |
| SCHEMBL1902209 | 0.89 | CYP1A2 (0.45) | PTGDR2MTNR1AMTNR1BNPC1RAB9A | |
| SCHEMBL1900836 | 0.88 | MTNR1A (0.43) | PTGDR2MTNR1AMTNR1BNPC1RAB9A | |
| SCHEMBL1900833 | 0.88 | MTNR1A (0.43) | PTGDR2MTNR1AMTNR1BNPC1RAB9A | |
| SCHEMBL1902517 | 0.88 | PTGDR2 (0.51) | HPGDALDH1A1PTGDR2MTNR1AMTNR1B | |
| SCHEMBL1902518 | 0.88 | PTGDR2 (0.51) | HPGDALDH1A1PTGDR2MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2051962-B1 | (3-AMINO-1,2,3,4-TETRAHYDRO-9H-CARBAZOL-9-YL)-ACETIC ACID DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2011-10-26 | — | — | EP | disclosed |