Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1900071 | 1.00 | RAB9A (0.44) | RAB9ANPC1PTGDR2ALDH1A1LMNA | |
| SCHEMBL1902893 | 0.94 | MEN1 (0.43) | RAB9ANPC1PTGDR2ALDH1A1LMNA | |
| SCHEMBL2491209 | 0.94 | HPGD (0.43) | RAB9ANPC1PTGDR2ALDH1A1LMNA | |
| SCHEMBL1902531 | 0.94 | HPGD (0.43) | RAB9ANPC1PTGDR2ALDH1A1LMNA | |
| SCHEMBL1904951 | 0.90 | PTGDR2 (0.51) | RAB9ANPC1PTGDR2ALDH1A1HPGD | |
| SCHEMBL1904953 | 0.90 | PTGDR2 (0.51) | RAB9ANPC1PTGDR2ALDH1A1HPGD | |
| SCHEMBL1901494 | 0.88 | MCHR1 (0.41) | PTGDR2 | |
| SCHEMBL1901492 | 0.88 | MCHR1 (0.41) | PTGDR2 | |
| SCHEMBL1902209 | 0.87 | CYP1A2 (0.45) | RAB9ANPC1PTGDR2LMNASMN1; SMN2 | |
| SCHEMBL1902210 | 0.87 | CYP1A2 (0.45) | RAB9ANPC1PTGDR2LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2051962-B1 | (3-AMINO-1,2,3,4-TETRAHYDRO-9H-CARBAZOL-9-YL)-ACETIC ACID DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2011-10-26 | — | — | EP | disclosed |