Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SHBG | P04278 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18526557 | 1.00 | DRD2 (0.36) | DRD2DRD3HRH3OPRM1OPRL1 | |
| SCHEMBL20178652 | 0.88 | SHBG (0.39) | DRD2DRD3HRH3OPRM1OPRL1 | |
| SCHEMBL10236309 | 0.88 | SHBG (0.39) | DRD2DRD3HRH3OPRM1OPRL1 | |
| SCHEMBL25707668 | 0.85 | HRH3 (0.37) | DRD2DRD3HRH3OPRM1OPRL1 | |
| SCHEMBL18885421 | 0.84 | SHBG (0.34) | DRD2DRD3HRH3SHBGTSHR | |
| SCHEMBL18526364 | 0.83 | UBE2M (0.33) | OPRM1OPRL1 | |
| SCHEMBL24783210 | 0.82 | HRH3 (0.35) | DRD2DRD3HRH3OPRM1OPRL1 | |
| SCHEMBL13910210 | 0.79 | ALDH1A1 (0.36) | DRD2DRD3HRH3ALDH1A1 | |
| SCHEMBL23231154 | 0.79 | ALDH1A1 (0.36) | DRD2DRD3HRH3ALDH1A1 | |
| SCHEMBL2603329 | 0.79 | ALDH1A1 (0.36) | DRD2DRD3HRH3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3601297-B9 | COMPOUNDS THAT INHIBIT MCL-1 PROTEIN | AMGEN INC (US) | 2023-05-24 | — | — | EP | disclosed |